Mark S Segal

Mark S Segal, M.D., PH.D.

Senior Associate Dean For Faculty Affairs And Professional Development

Department: MD-NEPHROLOGY
Business Phone: (352) 273-8821
Business Email: segalms@medicine.ufl.edu

Teaching Profile

Courses Taught
2019-2020
PAS5010 Intro to Medicine 1
2014-2021
MDU4010 Cell Biology Seminar
2018
MDC7200 Medicine Clerkship
2016
BMS4905 Medical Sciences Senior Research
2014-2016
MDT7200 Elect Top/Medicine
2015
GMS7093 Introduction to Clinical and Translational Research
2015
BMS6638C Kidney & Urinary Tract
2015
GMS6683 Fundamentals of Vascular Physiology and Pathology
2006-2007,2009-2012,2012
MEL4003 Cell Biology Seminar

Board Certifications

  • Internal Medicine
    American Board of Internal Medicine
  • Nephrology
    American Board of Internal Medicine

Clinical Profile

Specialties
  • Medicine
Subspecialties
  • Nephrology
Areas of Interest
  • Chronic kidney disease
  • Glomerulonephritis
  • Kidney disease – resources
  • Lupus – resources
  • Lupus nephritis
  • Systemic lupus erythematosus

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-5502-2042

Publications

2022
Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis: A Prospective Observational Study.
Annals of surgery. 275(6):1184-1193 [DOI] 10.1097/SLA.0000000000004360. [PMID] 33196489.
2022
Early Biomarker Signatures in Surgical Sepsis.
The Journal of surgical research. 277:372-383 [DOI] 10.1016/j.jss.2022.04.052. [PMID] 35569215.
2022
Provision of Kidney Disease Education Service Is Associated with Improved Vascular Access Outcomes among US Incident Hemodialysis Patients.
Kidney360. 3(1):91-98 [DOI] 10.34067/KID.0004502021. [PMID] 35368570.
2021
Advancing Nephrology: Division Leaders Advise ASN.
Clinical journal of the American Society of Nephrology : CJASN. 16(2):319-327 [DOI] 10.2215/CJN.01550220. [PMID] 32792352.
2021
Association of early initiation of dialysis with all-cause and cardiovascular mortality: A propensity score weighted analysis of the United States Renal Data System.
Hemodialysis international. International Symposium on Home Hemodialysis. 25(2):188-197 [DOI] 10.1111/hdi.12912. [PMID] 33644974.
2021
Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial.
JAMA neurology. [DOI] 10.1001/jamaneurol.2021.0178. [PMID] 33683313.
2021
Association of persistent acute kidney injury and renal recovery with mortality in hospitalised patients.
BMJ health & care informatics. 28(1) [DOI] 10.1136/bmjhci-2021-100458. [PMID] 34876451.
2021
Circulating endothelial cells as predictor of long-term mortality and adverse cardiovascular outcomes in hemodialysis patients.
Seminars in dialysis. 34(2):163-169 [DOI] 10.1111/sdi.12943. [PMID] 33280176.
2021
LC-MS lipidomics of renal biopsies for the diagnosis of Fabry disease.
Journal of mass spectrometry and advances in the clinical lab. 22:71-78 [DOI] 10.1016/j.jmsacl.2021.11.004. [PMID] 34918004.
2021
Management of Cardiovascular Disease in Kidney Disease Study: Rationale and Design.
American journal of nephrology. 52(1):36-44 [DOI] 10.1159/000513567. [PMID] 33640890.
2021
Nonatherosclerotic Vascular Abnormalities Associated with Chronic Kidney Disease.
Cardiology clinics. 39(3):415-425 [DOI] 10.1016/j.ccl.2021.04.012. [PMID] 34247754.
2021
Pro Re Nata Antihypertensive Medications and Adverse Outcomes in Hospitalized Patients: A Propensity-Matched Cohort Study.
Hypertension (Dallas, Tex. : 1979). 78(2):516-524 [DOI] 10.1161/HYPERTENSIONAHA.121.17279. [PMID] 34148363.
2021
Relationships between reproductive hormones and maternal pregnancy physiology in women conceiving with or without in vitro fertilization.
American journal of physiology. Regulatory, integrative and comparative physiology. 321(3):R454-R468 [DOI] 10.1152/ajpregu.00174.2020. [PMID] 34346723.
2021
Utilization of CMS pre-ESRD Kidney Disease Education services and its associations with the home dialysis therapies.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 41(5):453-462 [DOI] 10.1177/0896860820975586. [PMID] 33258420.
2020
A Word of Caution in the Use of Hydroxychloroquine in the Elderly COVID-19 Population.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). 9(4):374-375 [DOI] 10.1097/APO.0000000000000314. [PMID] 32740071.
2020
Discovery and Validation of Urinary Molecular Signature of Early Sepsis.
Critical care explorations. 2(10) [DOI] 10.1097/CCE.0000000000000195. [PMID] 33063018.
2020
Engineering magnetic nanoparticles and their integration with microfluidics for cell isolation.
Journal of colloid and interface science. 564:204-215 [DOI] 10.1016/j.jcis.2019.12.092. [PMID] 31911225.
2020
Graft-versus-host disease of the kidney.
Hematology/oncology and stem cell therapy. 13(3):178-179 [DOI] 10.1016/j.hemonc.2019.01.003. [PMID] 30807739.
2020
Maternal endothelial function, circulating endothelial cells, and endothelial progenitor cells in pregnancies conceived with or without in vitro fertilization.
American journal of physiology. Regulatory, integrative and comparative physiology. 318(6):R1091-R1102 [DOI] 10.1152/ajpregu.00015.2020. [PMID] 32349514.
2020
Roxadustat for Anemia in Patients with Chronic Kidney Disease.
The New England journal of medicine. 383(1) [DOI] 10.1056/NEJMc1913712. [PMID] 32610000.
2020
Tubular Biomarkers and Chronic Kidney Disease Progression in SPRINT Participants.
American journal of nephrology. 51(10):797-805 [DOI] 10.1159/000509978. [PMID] 32906135.
2019
Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease.
Journal of clinical hypertension (Greenwich, Conn.). 21(1):91-101 [DOI] 10.1111/jch.13429. [PMID] 30427124.
2019
Increased Preeclampsia Risk and Reduced Aortic Compliance With In Vitro Fertilization Cycles in the Absence of a Corpus Luteum.
Hypertension (Dallas, Tex. : 1979). 73(3):640-649 [DOI] 10.1161/HYPERTENSIONAHA.118.12043. [PMID] 30636552.
2019
Integrating Point-of-Care Ultrasonography Into Nephrology Fellowship Training: A Model Curriculum.
American journal of kidney diseases : the official journal of the National Kidney Foundation. 74(1):1-5 [DOI] 10.1053/j.ajkd.2019.02.002. [PMID] 30910369.
2019
Maternal Cardiovascular Dysregulation During Early Pregnancy After In Vitro Fertilization Cycles in the Absence of a Corpus Luteum.
Hypertension (Dallas, Tex. : 1979). 74(3):705-715 [DOI] 10.1161/HYPERTENSIONAHA.119.13015. [PMID] 31352818.
2019
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Critical care (London, England). 23(1) [DOI] 10.1186/s13054-019-2628-x. [PMID] 31722736.
2019
Opioid Safety and Concomitant Benzodiazepine Use in End-Stage Renal Disease Patients.
Pain research & management. 2019 [DOI] 10.1155/2019/3865924. [PMID] 31772694.
2019
Potential influence of the corpus luteum on circulating reproductive and volume regulatory hormones, angiogenic and immunoregulatory factors in pregnant women.
American journal of physiology. Endocrinology and metabolism. 317(4):E677-E685 [DOI] 10.1152/ajpendo.00225.2019. [PMID] 31408378.
2019
Serum Sodium and Pulse Pressure in SPRINT.
American journal of hypertension. 32(7):649-656 [DOI] 10.1093/ajh/hpz055. [PMID] 30977767.
2019
The utility of trough mycophenolic acid levels for the management of lupus nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 34(1):83-89 [DOI] 10.1093/ndt/gfy026. [PMID] 29548021.
2018
Activation of the β-common receptor by erythropoietin impairs acetylcholine-mediated vasodilation in mouse mesenteric arterioles.
Physiological reports. 6(12) [DOI] 10.14814/phy2.13751. [PMID] 29939494.
2018
Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.
The journal of trauma and acute care surgery. 84(2):342-349 [DOI] 10.1097/TA.0000000000001758. [PMID] 29251709.
2018
Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome.
Frontiers in immunology. 9 [DOI] 10.3389/fimmu.2018.01511. [PMID] 30013565.
2018
Computational design and experimental characterization of a novel β-common receptor inhibitory peptide.
Peptides. 104:1-6 [DOI] 10.1016/j.peptides.2018.04.001. [PMID] 29635062.
2018
Development of a personalized diagnostic model for kidney stone disease tailored to acute care by integrating large clinical, demographics and laboratory data: the diagnostic acute care algorithm – kidney stones (DACA-KS).
BMC medical informatics and decision making. 18(1) [DOI] 10.1186/s12911-018-0652-4. [PMID] 30119627.
2018
Gender, blood pressure, and cardiovascular and renal outcomes in adults with hypertension from the Systolic Blood Pressure Intervention Trial.
Journal of hypertension. 36(4):904-915 [DOI] 10.1097/HJH.0000000000001619. [PMID] 29493562.
2018
Not all that is red is blood: a curious case of chromaturia.
Clinical case reports. 6(6):1179-1180 [DOI] 10.1002/ccr3.1514. [PMID] 29881591.
2018
Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery.
Surgery. 164(2):178-184 [DOI] 10.1016/j.surg.2018.04.011. [PMID] 29807651.
2018
Pulse pressure, arterial stiffening, and the efficacy of renin-angiotensin system inhibitor combinations.
Journal of human hypertension. 32(2):165-166 [DOI] 10.1038/s41371-017-0014-1. [PMID] 29230003.
2018
Wave reflections and global arterial compliance during normal human pregnancy.
Physiological reports. 6(24) [DOI] 10.14814/phy2.13947. [PMID] 30578623.
2017
Case Report of Spontaneous Remission of Biopsy-Proven Idiopathic Immune Complex-Mediated Membranoproliferative Glomerulonephritis.
Case reports in nephrology and dialysis. 7(2):81-90 [DOI] 10.1159/000477660. [PMID] 28868298.
2017
Comparison of multiple non-invasive methods of measuring cardiac output during pregnancy reveals marked heterogeneity in the magnitude of cardiac output change between women.
Physiological reports. 5(8) [DOI] 10.14814/phy2.13223. [PMID] 28438984.
2017
Conditional Deletion of Bmal1 Accentuates Microvascular and Macrovascular Injury
The American Journal Of Pathology. 187(6):1426-1435 [DOI] 10.1016/j.ajpath.2017.02.014. [PMID] 28432873.
2017
Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients.
BMJ open. 7(7) [DOI] 10.1136/bmjopen-2016-015136. [PMID] 28765125.
2017
Tubulointerstitial Nephritis in Sjögren Syndrome Treated With Mycophenolate Mofetil.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 23(7):402-403 [DOI] 10.1097/RHU.0000000000000595. [PMID] 28937480.
2017
Using Organizational Philosophy to Create a Self-Sustaining Compensation Plan Without Harming Academic Missions.
Academic medicine : journal of the Association of American Medical Colleges. 92(8):1133-1137 [DOI] 10.1097/ACM.0000000000001484. [PMID] 28746136.
2016
A case of isolated renal involvement of polyarteritis nodosa successfully treated with steroid monotherapy.
BMJ case reports. 2016 [DOI] 10.1136/bcr-2016-215702. [PMID] 27440849.
2016
A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM.
Arthritis & rheumatology (Hoboken, N.J.). 68(12):2917-2928 [DOI] 10.1002/art.39781. [PMID] 27274010.
2016
Acute and Chronic Kidney Disease and Cardiovascular Mortality After Major Surgery.
Annals of surgery. 264(6):987-996 [PMID] 26756753.
2016
Effects of Long-Term Type I Interferon on the Arterial Wall and Smooth Muscle Progenitor Cells Differentiation.
Arteriosclerosis, thrombosis, and vascular biology. 36(2):266-73 [DOI] 10.1161/ATVBAHA.115.306767. [PMID] 26634654.
2016
Nebivolol Effects on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients.
Journal of clinical hypertension (Greenwich, Conn.). 18(8):741-9 [DOI] 10.1111/jch.12745. [PMID] 26692375.
2015
Cost and Mortality Associated With Postoperative Acute Kidney Injury.
Annals of surgery. 261(6):1207-14 [DOI] 10.1097/SLA.0000000000000732. [PMID] 24887982.
2015
DNA Aptamer Assembly as a Vascular Endothelial Growth Factor Receptor Agonist.
Nucleic acid therapeutics. 25(5):227-34 [DOI] 10.1089/nat.2014.0519. [PMID] 26125598.
2015
Early Angiogenic Balance and Adverse Long-Term Outcomes in Sepsis
Shock. 43(6, 1)
2015
Fiber supplementation lowers plasma p-cresol in chronic kidney disease patients.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 25(3):316-20 [DOI] 10.1053/j.jrn.2014.09.002. [PMID] 25446837.
2015
Heart failure and chronic kidney disease: should we use spironolactone?
The American journal of the medical sciences. 350(2):147-51 [DOI] 10.1097/MAJ.0000000000000514. [PMID] 26086152.
2015
Higher levels of adiponectin in vascular endothelial cells are associated with greater brachial artery flow-mediated dilation in older adults.
Experimental gerontology. 63:1-7 [DOI] 10.1016/j.exger.2014.12.018. [PMID] 25572013.
2015
Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease.
PloS one. 10(9) [DOI] 10.1371/journal.pone.0139226. [PMID] 26414017.
2015
Mild renal dysfunction and long-term adverse outcomes in women with chest pain: results from the National Heart, Lung, and Blood Institute-sponsored Women’s Ischemia Syndrome Evaluation (WISE).
American heart journal. 169(3):412-8 [DOI] 10.1016/j.ahj.2014.12.010. [PMID] 25728732.
2015
Renal function and coronary microvascular dysfunction in women with symptoms/signs of ischemia.
PloS one. 10(5) [DOI] 10.1371/journal.pone.0125374. [PMID] 25951606.
2015
The effect of the addition of allopurinol on blood pressure control in African Americans treated with a thiazide-like diuretic.
Journal of the American Society of Hypertension : JASH. 9(8):610-619.e1 [DOI] 10.1016/j.jash.2015.05.009. [PMID] 26140739.
2014
End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.
Arthritis & rheumatology (Hoboken, N.J.). 66(2):390-6 [DOI] 10.1002/art.38220. [PMID] 24504811.
2014
Evidence for Impaired Maternal Circulatory Adaptations in Pregnancies Conceived Using Donor Eggs
Reproductive Sciences. 21(3, S)
2014
Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection.
The Journal of infectious diseases. 209(10):1602-12 [DOI] 10.1093/infdis/jit801. [PMID] 24325966.
2014
Uric acid inhibition of dipeptidyl peptidase IV in vitro is dependent on the intracellular formation of triuret.
Experimental cell research. 326(1):136-42 [DOI] 10.1016/j.yexcr.2014.05.025. [PMID] 24925478.
2014
Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms.
PloS one. 9(4) [DOI] 10.1371/journal.pone.0093965. [PMID] 24713821.
2013
Evaluation of stability and sensitivity of cell fluorescent labels when used for cell migration.
Journal of fluorescence. 23(5):975-87 [DOI] 10.1007/s10895-013-1224-8. [PMID] 23722994.
2013
Foods with added fiber lower serum creatinine levels in patients with chronic kidney disease.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 23(2):e29-32 [DOI] 10.1053/j.jrn.2012.04.002. [PMID] 22739658.
2013
Global RNA structure analysis of poliovirus identifies a conserved RNA structure involved in viral replication and infectivity.
Journal of virology. 87(21):11670-83 [DOI] 10.1128/JVI.01560-13. [PMID] 23966409.
2013
Long-Term Administration of Type-I Interferon Leads To Premature Atherosclerosis
Circulation. 128(22, S)
2013
Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model.
Diabetologia. 56(3):644-53 [DOI] 10.1007/s00125-012-2781-0. [PMID] 23192694.
2013
Lupus nephritis and end-stage kidney disease.
The American journal of the medical sciences. 346(4):319-23 [DOI] 10.1097/MAJ.0b013e31827f4ee3. [PMID] 23370533.
2013
Mild Renal Insufficiency Is An Independent Predictor of Coronary Microvascular Dysfunction Among Women With Symptoms/Signs of Ischemia: a Report From the Women’s Ischemia Syndrome Evaluation (Wise)
Circulation. 128(22, S)
2013
Mild Renal Insufficiency Predicts Mortality and Adverse Events in Women With Cardiac Ischemia, Independent of the Underlying Obstructive Coronary Artery Disease
Circulation. 128(22, S)
2013
Mineralocorticoid receptors modulate vascular endothelial function in human obesity.
Clinical science (London, England : 1979). 125(11):513-20 [DOI] 10.1042/CS20130200. [PMID] 23786536.
2013
National surgical quality improvement program underestimates the risk associated with mild and moderate postoperative acute kidney injury.
Critical care medicine. 41(11):2570-83 [DOI] 10.1097/CCM.0b013e31829860fc. [PMID] 23928835.
2013
Number and function of bone-marrow derived angiogenic cells and coronary flow reserve in women without obstructive coronary artery disease: a substudy of the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE).
PloS one. 8(12) [DOI] 10.1371/journal.pone.0081595. [PMID] 24312563.
2013
Racial and socioeconomic disparities in the allocation of expanded criteria donor kidneys.
Clinical journal of the American Society of Nephrology : CJASN. 8(12):2158-64 [DOI] 10.2215/CJN.01430213. [PMID] 24115196.
2013
The role of uric acid in the pathogenesis of human cardiovascular disease.
Heart (British Cardiac Society). 99(11):759-66 [DOI] 10.1136/heartjnl-2012-302535. [PMID] 23343689.
2012
A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies.
Lancet (London, England). 379(9818):823-32 [DOI] 10.1016/S0140-6736(11)61941-7. [PMID] 22285053.
2012
Apolipoprotein L1 Risk Variants Underlie Racial Disparities in Lupus Nephritis-Induced End-Stage Renal Disease
Arthritis and Rheumatism. 64
2012
Creatinine Clearance Predicts Poor Outcome in Emergency Department Presentation of Pediatric Sepsis
Critical Care Medicine. 40:U141-U142
2012
Effect of Postoperative Acute Kidney Injury On Hospital Cost
Critical Care Medicine. 40
2012
Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects.
Metabolism: clinical and experimental. 61(5):641-51 [DOI] 10.1016/j.metabol.2011.09.013. [PMID] 22152650.
2012
Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children’s Oncology Group.
International journal of molecular imaging. 2012 [DOI] 10.1155/2012/250834. [PMID] 23050139.
2012
Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice.
Blood. 119(2):629-36 [DOI] 10.1182/blood-2011-04-346007. [PMID] 22028476.
2011
A Novel Circulating Cxcr5-Cd20++ B Cell Compartment in Patients With Systemic Lupus Erythematosus
Arthritis and Rheumatism. 63
2011
Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients.
Clinical lung cancer. 12(4):237-44 [DOI] 10.1016/j.cllc.2011.03.025. [PMID] 21726823.
2011
Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical study.
Arthritis research & therapy. 13(3) [DOI] 10.1186/ar3334. [PMID] 21569292.
2011
Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Nature chemical biology. 7(12):925-34 [DOI] 10.1038/nchembio.694. [PMID] 22037470.
2011
Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide.
Endocrinology. 152(7):2786-96 [DOI] 10.1210/en.2010-1126. [PMID] 21558316.
2011
Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan natives in the Indian Health Service.
Digestive diseases and sciences. 56(7):2104-13 [DOI] 10.1007/s10620-010-1528-3. [PMID] 21234688.
2011
Sequence-based classification using discriminatory motif feature selection.
PloS one. 6(11) [DOI] 10.1371/journal.pone.0027382. [PMID] 22102890.
2011
The relative importance of predictors of body mass index change, overweight and obesity in adolescent girls.
International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity. 6(2-2):e233-42 [DOI] 10.3109/17477166.2010.545410. [PMID] 21244233.
2010
Cryoglobulinemic Mpgn in a Patient With Scleroderma and Sjogren’s Syndrome
. 55
2010
Endogenous type-I interferon activity is not associated with depression or fatigue in systemic lupus erythematosus.
Journal of neuroimmunology. 223(1-2):13-9 [DOI] 10.1016/j.jneuroim.2010.03.018. [PMID] 20416954.
2010
Endothelial progenitor cells and endothelial vesicles – what is the significance for patients with chronic kidney disease?
Blood purification. 29(2):158-62 [DOI] 10.1159/000245643. [PMID] 20093822.
2010
Induction of nitric oxide by erythropoietin is mediated by the {beta} common receptor and requires interaction with VEGF receptor 2.
Blood. 115(4):896-905 [DOI] 10.1182/blood-2009-04-216432. [PMID] 19965681.
2010
Monocyte surface expression of Fcgamma receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus.
Arthritis research & therapy. 12(3) [DOI] 10.1186/ar3017. [PMID] 20478071.
2010
Prospective assessment of inpatient gastrointestinal consultation requests in an academic teaching hospital.
The American journal of gastroenterology. 105(3):484-9 [DOI] 10.1038/ajg.2009.686. [PMID] 20203634.
2010
Uric acid and hypertension: cause or effect?
Current rheumatology reports. 12(2):108-17 [DOI] 10.1007/s11926-010-0094-1. [PMID] 20425019.
2009
Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery.
Circulation. 119(18):2444-53 [DOI] 10.1161/CIRCULATIONAHA.108.800011. [PMID] 19398670.
2009
Altered Homeostasis of Cd4+Memory T Cells in Peripheral Blood of Active Lupus Patients
Journal of Allergy and Clinical Immunology. 123(2):340-S91 [DOI] 10.1016/j.jaci.2008.12.324.
2009
Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress.
Neurochemistry international. 54(2):106-10 [DOI] 10.1016/j.neuint.2008.10.009. [PMID] 19041675.
2009
Citrulline dependence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus as a marker of deforming/erosive arthritis.
The Journal of rheumatology. 36(12):2682-90 [DOI] 10.3899/jrheum.090338. [PMID] 19884269.
2009
Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.
The Journal of experimental medicine. 206(13):2897-906 [DOI] 10.1084/jem.20090889. [PMID] 19934019.
2009
Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes?
Endocrine reviews. 30(1):96-116 [DOI] 10.1210/er.2008-0033. [PMID] 19151107.
2009
Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus.
Arthritis research & therapy. 11(1) [DOI] 10.1186/ar2590. [PMID] 19144150.
2009
Lambda chops: creation of site-directed mutants in insertable fragments utilizing Gateway technology.
Molecular biotechnology. 42(3):275-81 [DOI] 10.1007/s12033-009-9158-8. [PMID] 19301156.
2009
Long-term risk of mortality and acute kidney injury during hospitalization after major surgery.
Annals of surgery. 249(5):851-8 [DOI] 10.1097/SLA.0b013e3181a40a0b. [PMID] 19387314.
2009
Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice.
The American journal of pathology. 174(4):1221-9 [DOI] 10.2353/ajpath.2009.080605. [PMID] 19246639.
2009
Mechanisms of Relaxin-Induced Rapid Arterial Relaxation.
Reproductive Sciences. 16
2009
Role of relaxin in maternal systemic and renal vascular adaptations during gestation.
Annals of the New York Academy of Sciences. 1160:304-12 [DOI] 10.1111/j.1749-6632.2009.03829.x. [PMID] 19416209.
2009
Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(1-2):65-70 [DOI] 10.1016/j.jchromb.2008.11.029. [PMID] 19081307.
2009
The Erythropoietin Heterodimeric Beta Common Receptor Is in a Complex With and Requires Vegfr2 for Downstream Signaling
Circulation. 120
2009
Urinary CD80 excretion increases in idiopathic minimal-change disease.
Journal of the American Society of Nephrology : JASN. 20(2):260-6 [DOI] 10.1681/ASN.2007080836. [PMID] 19056875.
2008
A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(17):5565-70 [DOI] 10.1158/1078-0432.CCR-08-0544. [PMID] 18765549.
2008
Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes.
Diabetes. 57(9):2488-94 [DOI] 10.2337/db08-0381. [PMID] 18559661.
2008
How safe is fructose for persons with or without diabetes?
The American journal of clinical nutrition. 88(5):1189-90 [PMID] 18996851.
2008
Long-term engraftment of bone marrow-derived cells in the intimal hyperplasia lesion of autologous vein grafts.
The American journal of pathology. 172(3):839-48 [DOI] 10.2353/ajpath.2008.070840. [PMID] 18276778.
2008
No Unique Role for Fructose Sweeteners in Obesity Or Cardiorenal Disease – Reply
American Journal of Clinical Nutrition. 87:1063-1064
2008
Simple, defensible sample sizes based on cost efficiency.
Biometrics. 64(2):577-85; discussion 586 [DOI] 10.1111/j.1541-0420.2008.01004_1.x. [PMID] 18482055.
2008
Tacrolimus rescue therapy in resistant or relapsing cases of primary glomerulonephritis.
Journal of nephrology. 21(5):713-21 [PMID] 18949726.
2007
A breakthrough in diabetic nephropathy: the role of endothelial dysfunction.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 22(10):2775-7 [PMID] 17595179.
2007
Autoantibodies to RNA helicase A: a new serologic marker of early lupus.
Arthritis and rheumatism. 56(2):596-604 [PMID] 17265494.
2007
Is the fructose index more relevant with regards to cardiovascular disease than the glycemic index?
European journal of nutrition. 46(7):406-17 [PMID] 17763967.
2007
Mitomycin- and calcineurin-associated HUS, endothelial dysfunction and endothelial repair: a new paradigm for the puzzle?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 22(2):617-20 [PMID] 17041000.
2007
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
The American journal of clinical nutrition. 86(4):899-906 [PMID] 17921363.
2007
Retinal and choroidal microangiopathies: therapeutic opportunities.
Microvascular research. 74(2-3):131-44 [PMID] 17585951.
2007
Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus.
Arthritis and rheumatism. 56(11):3759-69 [PMID] 17968925.
2007
Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2′-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress.
Journal of chromatography. A. 1167(1):54-62 [PMID] 17765254.
2006
A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome.
Pediatric nephrology (Berlin, Germany). 21(5):603-10 [PMID] 16525836.
2006
Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases.
Arthritis research & therapy. 8(4) [PMID] 16846524.
2006
Development and validation of a prognostic index for 4-year mortality in older adults.
JAMA. 295(7):801-8 [PMID] 16478903.
2006
Endothelial health and diversity in the kidney.
Journal of the American Society of Nephrology : JASN. 17(2):323-4 [PMID] 16434502.
2006
Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity.
AIDS (London, England). 20(16):2123-5 [PMID] 17053362.
2006
Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes.
Diabetes. 55(1):102-9 [PMID] 16380482.
2006
Short-term atorvastatin treatment enhances specific antibody production following tetanus toxoid vaccination in healthy volunteers.
Vaccine. 24(19):4035-40 [PMID] 16464519.
2006
Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease.
Kidney international. 69(10):1722-5 [PMID] 16598194.
2006
Urinary biomarkers in lupus nephritis.
Autoimmunity reviews. 5(6):383-8 [PMID] 16890891.
2005
A novel mouse model of autologous venous graft intimal hyperplasia.
The Journal of surgical research. 126(1):106-13 [PMID] 15916983.
2005
Analysis of a splice array experiment elucidates roles of chromatin elongation factor Spt4-5 in splicing.
PLoS computational biology. 1(4) [PMID] 16172632.
2005
Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus.
Clinical immunology (Orlando, Fla.). 117(3):238-50 [PMID] 16126005.
2005
Circulating endothelial cells are associated with future vascular events in hemodialysis patients.
Kidney international. 67(3):1078-83 [PMID] 15698448.
2005
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
The New England journal of medicine. 352(15):1529-38 [PMID] 15829534.
2005
Essential hypertension, progressive renal disease, and uric acid: a pathogenetic link?
Journal of the American Society of Nephrology : JASN. 16(7):1909-19 [PMID] 15843466.
2005
High sensitivity C-reactive protein in systemic lupus erythematosus: relation to disease activity, clinical presentation and implications for cardiovascular risk.
Lupus. 14(8):576-82 [PMID] 16175928.
2005
SDF-1 is both necessary and sufficient to promote proliferative retinopathy.
The Journal of clinical investigation. 115(1):86-93 [PMID] 15630447.
2004
Diuretic-induced hyperuricemia does not decrease cardiovascular risk.
Journal of hypertension. 22(7):1415-7; author reply 1417 [PMID] 15201561.
2004
Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection.
The Journal of infectious diseases. 190(2):251-6 [PMID] 15216458.
2004
Management and outcomes of care of fever in early infancy.
JAMA. 291(10):1203-12 [PMID] 15010441.
2004
Real-time analysis of apoptosis in vivo.
Methods in cell biology. 75:343-54 [PMID] 15603432.
2004
Strong association of a functional polymorphism in the monocyte chemoattractant protein 1 promoter gene with lupus nephritis.
Arthritis and rheumatism. 50(6):1842-9 [PMID] 15188361.
2004
The 1.4-MDa apoptosome is a critical intermediate in apoptosome maturation.
American journal of physiology. Cell physiology. 287(3):C664-72 [PMID] 15128503.
2004
Thrombotic microangiopathy associated with unusual viral sequences in HIV-1-positive patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 19(5):1129-35 [PMID] 14993479.
2004
Vitreous levels of vascular endothelial growth factor and stromal-derived factor 1 in patients with diabetic retinopathy and cystoid macular edema before and after intraocular injection of triamcinolone.
Archives of ophthalmology (Chicago, Ill. : 1960). 122(12):1801-7 [PMID] 15596583.
2003
Circulating endothelial cells as potential markers of the state of the endothelium in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation. 42(4):704-12 [PMID] 14520620.
2003
Factors associated with future amputation among patients undergoing hemodialysis: results from the Dialysis Morbidity and Mortality Study Waves 3 and 4.
American journal of kidney diseases : the official journal of the National Kidney Foundation. 41(1):162-70 [PMID] 12500233.
2003
Intimal exuberance: veins in jeopardy.
The American journal of pathology. 162(6):1759-61 [PMID] 12759233.
2002
Circulating endothelial cells: tea leaves for renal disease.
American journal of physiology. Renal physiology. 283(1):F11-9 [PMID] 12060582.
2002
Marker for real-time analysis of caspase activity in intact cells.
BioTechniques. 33(6):1284-7, 1289 [PMID] 12503313.
2001
Effect of pH, ionic charge, and osmolality on cytochrome c-mediated caspase-3 activity.
American journal of physiology. Cell physiology. 281(4):C1196-204 [PMID] 11546656.
2000
Brain and CSF entry of the novel non-nucleoside reverse transcriptase inhibitor, GW420867X.
Neuroreport. 11(17):3811-5 [PMID] 11117496.
1999
Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin.
Biochemical and biophysical research communications. 255(3):735-9 [PMID] 10049780.
1999
Endostatin induces endothelial cell apoptosis.
The Journal of biological chemistry. 274(17):11721-6 [PMID] 10206987.
1999
Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells.
Biochemical and biophysical research communications. 258(3):668-73 [PMID] 10329443.
1998
Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities.
JAMA. 280(17):1510-7 [PMID] 9809732.
1997
Association between lifetime ambient ozone exposure and pulmonary function in college freshmen–results of a pilot study.
Environmental research. 72(1):8-23 [PMID] 9012368.
1997
Temporal trends and factors associated with survival after Pneumocystis carinii pneumonia in California, 1983-1992.
American journal of epidemiology. 146(2):115-27 [PMID] 9230773.
1996
Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro.
Mechanisms of development. 59(1):89-102 [PMID] 8892235.
1993
Age-related cognitive deficits in rats are associated with a combined loss of cholinergic and serotonergic functions.
Annals of the New York Academy of Sciences. 695:254-7 [PMID] 8239292.
1993
Assessing selfcare status in quadriplegia: comparison of the quadriplegia index of function (QIF) and the functional independence measure (FIM).
Paraplegia. 31(4):225-33 [PMID] 8493037.
1992
Correlates of knee pain among US adults with and without radiographic knee osteoarthritis.
The Journal of rheumatology. 19(12):1943-9 [PMID] 1294744.
1992
Disulfide bond formation during the folding of influenza virus hemagglutinin.
The Journal of cell biology. 118(2):227-44 [PMID] 1321156.
1992
Living arrangements and survival among middle-aged and older adults in the NHANES I epidemiologic follow-up study.
American journal of public health. 82(3):401-6 [PMID] 1536356.
1992
Serum beta 2-microglobulin and prediction of progression to AIDS in HIV infection.
Lancet (London, England). 339(8807):1436-40 [PMID] 1351128.
1991
A comparison of black and white family caregivers experience with dementia.
Journal of National Black Nurses' Association : JNBNA. 5(1):29-41 [PMID] 1885954.
1990
Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study.
Annals of epidemiology. 1(1):33-48 [PMID] 1669488.
1990
Deficits in AIDS incidence.
Journal of acquired immune deficiency syndromes. 3(8):832-5 [PMID] 2366150.
1990
The influence of oral potassium chloride on blood pressure in hypertensive men on a low-sodium diet.
The New England journal of medicine. 322(9):569-74 [PMID] 2406601.
1989
A “state model” of renal function in systemic lupus erythematosus: its value in the prediction of outcome in 292 patients.
The Journal of rheumatology. 16(1):29-35 [PMID] 2716006.
1975
Isoproterenol aerosols.
Annals of allergy. 34(4):205-9 [PMID] 1124859.
1975
The indiscriminate use of IPPB.
JAMA. 231(11):1141-2 [PMID] 1089818.
1964
CHRONIC BRONCHITIS.
The New England journal of medicine. 270:894-7 CONTD [PMID] 14112454.
1957
Long-term tracheostomy in extensive bilateral bronchiectasis.
The New England journal of medicine. 257(23):1108-11 [PMID] 13483897.
1956
The mechanics of breathing in different body positions. II. In cardiopulmonary disease.
The Journal of clinical investigation. 35(8):912-20 [PMID] 13345893.
1954
Orthoxine-theophylline for the relief of bronchial asthma.
The American journal of the medical sciences. 227(6):649-56 [PMID] 13158350.
1949
Evaluation of therapeutic substances employed for the relief of bronchospasm; aminophylline.
The Journal of clinical investigation. 28(5 Pt 2):1190-5 [PMID] 18139296.
1947
Penicillin inhalation therapy.
The New England journal of medicine. 236(4):132-8 [DOI] 10.1056/NEJM194701232360403. [PMID] 20280020.

Grants

Jul 2022 ACTIVE
Together: Transforming and Translating Discovery to Improve Health
Role: Faculty
Funding: NATL INST OF HLTH NCATS
Mar 2022 ACTIVE
A Phase 3, Randomized, Double-blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants Who Have Thrombotic Microangiopathy Associated With a Trigger
Role: Principal Investigator
Funding: PPD INVESTIGATOR SERVICES LLC via ALEXION PHARMACEUTICALS
Aug 2021 ACTIVE
Chronic aryl hydrocarbon receptor activation and skeletal myopathy in chronic kidney disease
Role: Other
Funding: NATL INST OF HLTH NIDDK
May 2020 ACTIVE
Development and Validation of Computational Algorithms to Assess Kidney Health in Electronic Health Records
Role: Other
Funding: NATL INST OF HLTH NIDDK
Dec 2019 ACTIVE
Molecular Mechanisms regulating peripheral arterial disease pathobiology in chronic kidney disease
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Oct 2019 ACTIVE
A multicentre international randomized parallel group double-blind placebo-controlled clinical trial of EMPAgliflozin once daily to assess cardio-renal outcomes in patients with chronic KIDNEY disease
Role: Principal Investigator
Funding: DUKE UNIVERSITY via UNIVERSITY OF OXFORD
Sep 2019 – May 2022
Sex Differences in Chronic and Acute Vascular Responses to Aerobic Exercise in Older Adults
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Dec 2018 ACTIVE
A multicentre international randomized parallel group double-blind placebo controlled clinical trial of EMPAgliflozin once daily to assess cardio-renal outcomes in patients with chronic KIDNEY disease
Role: Principal Investigator
Funding: DUKE UNIVERSITY via BOEHRINGER INGELHEIM INTL GmbH
Oct 2018 ACTIVE
A PHASE 2 PROSPECTIVE, RANDOMIZED, DOUBLE-ARM, DEFERRED TREATMENT, OPEN-LABEL, REPEAT DOSE, SAFETY AND EFFICACY STUDY OF AUTOLOGOUS NEO KIDNEY AUGMENT (NKA) IN SUBJECTS WITH TYPE 2 DIABETES AND CHRONIC KIDNEY DISEASE
Role: Principal Investigator
Funding: CTI CLINICAL TRIAL SERVICES via REGENMED (CAYMAN) LTD
Sep 2018 ACTIVE
Sparking Advancements in Genomic Medicine?
Role: Project Manager
Funding: NATL INST OF HLTH NHGRI
Aug 2018 ACTIVE
A PHASE II, OPEN-LABEL SAFETY AND TOLERABILITY STUDY OF AN AUTOLOGOUS NEO-KIDNEY AUGMENT (NKA) IN PATIENTS WITH TYPE 2 DIABETES AND CHRONIC KIDNEY DISEASE (REGEN-003)
Role: Principal Investigator
Funding: CTI CLINICAL TRIAL SERVICES via REGENMED (CAYMAN) LTD
Jun 2018 – May 2020
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Jun 2017 – Dec 2018
The SPRINT-Alzheimers, Seniors, and Kidney Study (SPRINT ASK)
Role: Principal Investigator
Funding: UNIV OF UTAH via NATL INST OF HLTH NIA
Jun 2017 – May 2018
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Apr 2017 – Apr 2022
A Phase 2 Prospective, Randomized, Double-Arm, Deferred Treatment, Open-Label, Repeat Dose, Safety and Efficacy Study of Autologous Neo-Kidney (NKA) in SUbjects with Type 2 Diabetes and Chronic Kidney Disease.
Role: Principal Investigator
Funding: CTI CLINICAL TRIAL SERVICES via REGENMED (CAYMAN) LTD
Sep 2016 – May 2022
Vascular Smooth Muscle Lysyl Oxidase Mediated Increase in Vessel Stiffness and its Effect on Rho-Kinase Mechanosensors: A Novel Mechanism of Atherosclerosis in Chronic Kidney Disease?
Role: Other
Funding: NATL INST OF HLTH NHLBI
Jun 2016 – May 2017
PICS: A New Horizon for Surgical Critical Care
Role: Project Manager
Funding: NATL INST OF HLTH NIGMS
Mar 2016 – Jun 2020
USING THORACIC IMPEDANCE TO PREDICT HYPERKALEMIA, ADVERSE EVENTS, AND PROGRESSION TOWARDS DRY WEIGHT DURING DIALYSIS.
Role: Principal Investigator
Funding: TOSENSE
Jul 2015 – Jan 2019
Potential Therapeutic Use of Relaxin in Healing Cranial Bone Defects
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION via US DEPT OF DEFENSE
Jun 2015 – Oct 2021
REnal TrAIning & reteNtion (RETAIN) Program
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jun 2015 – May 2016
PICS: A New Horizon for Surgical Critical Care
Role: Project Manager
Funding: NATL INST OF HLTH NIGMS
May 2015 – May 2017
Establishing an Interdisciplinary Team and Competitive Platform for a Quantum Grant titled "Dialysis-Like Cancer Cell Removal"
Role: Project Manager
Funding: UF DIV OF SPONSORED RESEARCH
Feb 2014 – Feb 2022
An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients with Atypical Hemolytic-Uremic Syndrome (aHUS Registry)
Role: Principal Investigator
Funding: ALEXION PHARMACEUTICALS
Feb 2014 – Feb 2022
An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients with Atypical Hemolytic-Uremic Syndrome (aHUS Registry)
Role: Principal Investigator
Funding: ALEXION PHARMACEUTICALS
Sep 2013 – Aug 2016
NO Dysregulation of the Peripheral Clock in Diabetic Complications
Role: Principal Investigator
Funding: INDIANA UNIV via NATL INST OF HLTH NIDDK
Feb 2012 – Feb 2018
A Multi-Center, Randomized, Controlled, Pivotal Study to Assess the Safety and Efficacy of A Selective Cytopheretic Device (SCD) In Patients with Acute Kidney Injury (AKI)
Role: Principal Investigator
Funding: CYTOPHERX
Sep 2011 – Sep 2016
Systolic Blood Pressure Intervention Trial (SPRINT) – Utah CCN
Role: Principal Investigator
Funding: UNIV OF UTAH via NATL INST OF HLTH
Aug 2011 – Feb 2020
Corpus Luteal Contribution to Maternal Pregnancy Physiology and Outcomes in ART
Role: Project Manager
Funding: NATL INST OF HLTH NICHD
Mar 2011 – May 2016
Otsuka Registry: An Observational prospective registry to identify demographic and clinical characteristics of patients hospitalized with euvolemic and hypervolemic hyponatremia and assess the comparative effectiveness of available treatments
Role: Principal Investigator
Funding: REGISTRAT
Jul 2007 – Dec 2020
Chair support from Johnson UFF 012724
Role: Principal Investigator
Funding: UF FOUNDATION
Apr 2007 – Dec 2020
Nephrology Research & Educ UFF Fund F001291
Role: Principal Investigator
Funding: UF FOUNDATION
Apr 2005 – Jun 2020
DCI Visiting Professor
Role: Principal Investigator
Funding: UF FOUNDATION
Oct 2002 – Oct 2019
Nephrology Hypertension Eminent Scholar
Role: Principal Investigator
Funding: UF FOUNDATION

Education

Fellowship – Nephrology
1998 · Beth Israel Deaconess Medical Center
Residency – Internal Medicine
1995 · Parkland Memorial Hospital
Internship – Internal Medicine
1993 · Parkland Memorial Hospital
Medical Degree
1992 · University of Southwestern
Bachelor of Science
1984 · Massachusetts Institute of Technology (MIT)

Contact Details

Phones:
Business:
(352) 273-8821
Emails:
Addresses:
Business Mailing:
PO BOX 100224
CG-98
GAINESVILLE FL 326100224
Business Street:
PO Box 100224
GAINESVILLE FL 32610