Mohan K Raizada

Mohan K Raizada,

DISTINGUISHED PROFESSOR

Department: MD-PHYSIOLOGY FUNCTIONAL GENOM
Business Phone: (352) 392-9299
Business Email: mraizada@ufl.edu

Teaching Profile

Courses Taught
2011-2015
DEN5120C Physiology
2014
PHA7980 Research for Doctoral Dissertation
2010
IDH4917 Undergrad Research

Publications

2022
Fecal matter transplant from Ace2 overexpressing mice counteracts chronic hypoxia-induced pulmonary hypertension.
Pulmonary circulation. 12(1) [DOI] 10.1002/pul2.12015. [PMID] 35506083.
2022
Gut Microbiome and Neuroinflammation in Hypertension.
Circulation research. 130(3):401-417 [DOI] 10.1161/CIRCRESAHA.121.319816. [PMID] 35113664.
2022
Identification of a Gut Commensal That Compromises the Blood Pressure-Lowering Effect of Ester Angiotensin-Converting Enzyme Inhibitors.
Hypertension (Dallas, Tex. : 1979). [DOI] 10.1161/HYPERTENSIONAHA.121.18711. [PMID] 35538603.
2021
Angiotensin-converting enzyme 2 and COVID-19 in cardiorenal diseases.
Clinical science (London, England : 1979). 135(1):1-17 [DOI] 10.1042/CS20200482. [PMID] 33399851.
2021
Butyrate Regulates COVID-19-Relevant Genes in Gut Epithelial Organoids From Normotensive Rats.
Hypertension (Dallas, Tex. : 1979). 77(2):e13-e16 [DOI] 10.1161/HYPERTENSIONAHA.120.16647. [PMID] 33439735.
2021
Depression phenotype identified by using single nucleotide exact amplicon sequence variants of the human gut microbiome.
Molecular psychiatry. 26(8):4277-4287 [DOI] 10.1038/s41380-020-0652-5. [PMID] 31988436.
2021
Depressive hypertension: A proposed human endotype of brain/gut microbiome dysbiosis.
American heart journal. 239:27-37 [DOI] 10.1016/j.ahj.2021.05.002. [PMID] 33984318.
2021
Distinct Gene Expression Profiles in Colonic Organoids from Normotensive and the Spontaneously Hypertensive Rats.
Cells. 10(6) [DOI] 10.3390/cells10061523. [PMID] 34204247.
2021
Functional heart recovery in an adult mammal, the spiny mouse.
International journal of cardiology. 338:196-203 [DOI] 10.1016/j.ijcard.2021.06.015. [PMID] 34126132.
2021
Gut-brain-bone marrow axis in hypertension.
Current opinion in nephrology and hypertension. 30(2):159-165 [DOI] 10.1097/MNH.0000000000000678. [PMID] 33394733.
2021
Potential of Minocycline for Treatment of Resistant Hypertension.
The American journal of cardiology. 156:147-149 [DOI] 10.1016/j.amjcard.2021.07.004. [PMID] 34348841.
2020
ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.
Hypertension (Dallas, Tex. : 1979). 76(3):651-661 [DOI] 10.1161/HYPERTENSIONAHA.120.15595. [PMID] 32783758.
2020
ACE2 as therapeutic agent.
Clinical science (London, England : 1979). 134(19):2581-2595 [DOI] 10.1042/CS20200570. [PMID] 33063820.
2020
Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension.
Hypertension (Dallas, Tex. : 1979). 75(4):1063-1071 [DOI] 10.1161/HYPERTENSIONAHA.119.14294. [PMID] 32088998.
2020
Angiotensin-(1-7) Expressed From Lactobacillus Bacteria Protect Diabetic Retina in Mice.
Translational vision science & technology. 9(13) [DOI] 10.1167/tvst.9.13.20. [PMID] 33344064.
2020
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2.
Circulation research. 126(10):1456-1474 [DOI] 10.1161/CIRCRESAHA.120.317015. [PMID] 32264791.
2020
Erratum: Expression of Human ACE2 in Lactobacillus and Beneficial Effects in Diabetic Retinopathy in Mice.
Molecular therapy. Methods & clinical development. 17 [DOI] 10.1016/j.omtm.2020.02.002. [PMID] 32128344.
2020
Gut Pathology and Its Rescue by ACE2 (Angiotensin-Converting Enzyme 2) in Hypoxia-Induced Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979). 76(1):206-216 [DOI] 10.1161/HYPERTENSIONAHA.120.14931. [PMID] 32418496.
2020
Maternal Treatment With Captopril Persistently Alters Gut-Brain Communication and Attenuates Hypertension of Male Offspring.
Hypertension (Dallas, Tex. : 1979). 75(5):1315-1324 [DOI] 10.1161/HYPERTENSIONAHA.120.14736. [PMID] 32200676.
2020
Mycophenolate Improves Brain-Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats.
Antioxidants (Basel, Switzerland). 9(12) [DOI] 10.3390/antiox9121199. [PMID] 33260593.
2020
Probiotic Bifidobacterium breve prevents DOCA-salt hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34(10):13626-13640 [DOI] 10.1096/fj.202001532R. [PMID] 32780919.
2020
Probiotics Prevent Dysbiosis and the Rise in Blood Pressure in Genetic Hypertension: Role of Short-Chain Fatty Acids.
Molecular nutrition & food research. 64(6) [DOI] 10.1002/mnfr.201900616. [PMID] 31953983.
2020
Pulmonary arterial hypertension-associated changes in gut pathology and microbiota.
ERJ open research. 6(3) [DOI] 10.1183/23120541.00253-2019. [PMID] 32743008.
2020
Pulmonary hypertension: Pathophysiology beyond the lung.
Pharmacological research. 151 [DOI] 10.1016/j.phrs.2019.104518. [PMID] 31730803.
2020
Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation.
Hypertension (Dallas, Tex. : 1979). 75(4):902-917 [DOI] 10.1161/HYPERTENSIONAHA.119.13887. [PMID] 32063061.
2020
Response by Gheblawi et al to Letter Regarding Article, “Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2”.
Circulation research. 127(2):e46-e47 [DOI] 10.1161/CIRCRESAHA.120.317332. [PMID] 32614719.
2020
SARS-CoV-2 Infections and ACE2: Clinical Outcomes Linked With Increased Morbidity and Mortality in Individuals With Diabetes.
Diabetes. 69(9):1875-1886 [DOI] 10.2337/dbi20-0019. [PMID] 32669391.
2020
SARS-CoV-2 Receptor ACE2 (Angiotensin-Converting Enzyme 2) Is Upregulated in Colonic Organoids From Hypertensive Rats.
Hypertension (Dallas, Tex. : 1979). 76(3):e26-e28 [DOI] 10.1161/HYPERTENSIONAHA.120.15725. [PMID] 32643416.
2020
Therapeutic Delivery of Ang(1-7) via Genetically Modified Probiotic: A Dosing Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(7):1299-1303 [DOI] 10.1093/gerona/glz222. [PMID] 31586210.
2020
Transcriptomic signature of gut microbiome-contacting cells in colon of spontaneously hypertensive rats.
Physiological genomics. 52(3):121-132 [DOI] 10.1152/physiolgenomics.00087.2019. [PMID] 31869283.
2020
Would Repurposing Minocycline Alleviate Neurologic Manifestations of COVID-19?
Frontiers in neuroscience. 14 [DOI] 10.3389/fnins.2020.577780. [PMID] 33117121.
2019
Chemokine signaling axis between endothelial and myeloid cells regulates development of pulmonary hypertension associated with pulmonary fibrosis and hypoxia.
American journal of physiology. Lung cellular and molecular physiology. 317(4):L434-L444 [DOI] 10.1152/ajplung.00156.2019. [PMID] 31364370.
2019
Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model.
Stem cells international. 2019 [DOI] 10.1155/2019/3945850. [PMID] 31781239.
2019
Critical Role of the Interaction Gut Microbiota – Sympathetic Nervous System in the Regulation of Blood Pressure.
Frontiers in physiology. 10 [DOI] 10.3389/fphys.2019.00231. [PMID] 30930793.
2019
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension.
American journal of physiology. Heart and circulatory physiology. 317(2):H279-H289 [DOI] 10.1152/ajpheart.00510.2018. [PMID] 31150271.
2019
Expression of Human ACE2 in Lactobacillus and Beneficial Effects in Diabetic Retinopathy in Mice.
Molecular therapy. Methods & clinical development. 14:161-170 [DOI] 10.1016/j.omtm.2019.06.007. [PMID] 31380462.
2019
Impaired Autonomic Nervous System-Microbiome Circuit in Hypertension.
Circulation research. 125(1):104-116 [DOI] 10.1161/CIRCRESAHA.119.313965. [PMID] 31219753.
2019
Microglial Cells Impact Gut Microbiota and Gut Pathology in Angiotensin II-Induced Hypertension.
Circulation research. 124(5):727-736 [DOI] 10.1161/CIRCRESAHA.118.313882. [PMID] 30612527.
2019
Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats.
Acta physiologica (Oxford, England). 227(1) [DOI] 10.1111/apha.13285. [PMID] 31004464.
2019
Sustained Captopril-Induced Reduction in Blood Pressure Is Associated With Alterations in Gut-Brain Axis in the Spontaneously Hypertensive Rat.
Journal of the American Heart Association. 8(4) [DOI] 10.1161/JAHA.118.010721. [PMID] 30755073.
2018
ACE2 and pACE2: A Pair of Aces for Pulmonary Arterial Hypertension Treatment?
American journal of respiratory and critical care medicine. 198(4):422-423 [DOI] 10.1164/rccm.201803-0569ED. [PMID] 29634285.
2018
Beneficial Effects of Angiotensin-(1-7) on CD34+ Cells From Patients With Heart Failure.
Journal of cardiovascular pharmacology. 71(3):155-159 [DOI] 10.1097/FJC.0000000000000556. [PMID] 29140957.
2018
Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.
Neuropharmacology. 133:85-93 [DOI] 10.1016/j.neuropharm.2018.01.025. [PMID] 29360543.
2018
Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure.
International journal of cardiology. 271:336-339 [DOI] 10.1016/j.ijcard.2018.04.074. [PMID] 30049487.
2018
Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure.
Clinical science (London, England : 1979). 132(6):701-718 [DOI] 10.1042/CS20180087. [PMID] 29507058.
2018
Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression.
Gut. 67(8):1555-1557 [DOI] 10.1136/gutjnl-2017-314759. [PMID] 28814485.
2018
Involvement of Microglial Cells in Hypoxia-induced Pulmonary Hypertension.
American journal of respiratory cell and molecular biology. 59(2):271-273 [DOI] 10.1165/rcmb.2018-0042LE. [PMID] 30067089.
2018
Involvement of Neuroinflammation in the Pathogenesis of Monocrotaline-Induced Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979). 71(6):1156-1163 [DOI] 10.1161/HYPERTENSIONAHA.118.10934. [PMID] 29712738.
2018
The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease.
Nature reviews. Nephrology. 14(7):442-456 [DOI] 10.1038/s41581-018-0018-2. [PMID] 29760448.
2018
The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury.
Frontiers in physiology. 9 [DOI] 10.3389/fphys.2018.00180. [PMID] 29636695.
2017
A Single Angiotensin II Hypertensive Stimulus Is Associated with Prolonged Neuronal and Immune System Activation in Wistar-Kyoto Rats.
Frontiers in physiology. 8 [DOI] 10.3389/fphys.2017.00592. [PMID] 28912720.
2017
Gut Microbiota: Potential for a Unifying Hypothesis for Prevention and Treatment of Hypertension.
Circulation research. 120(11):1724-1726 [DOI] 10.1161/CIRCRESAHA.117.310734. [PMID] 28546357.
2017
Hypertension-Linked Pathophysiological Alterations in the Gut.
Circulation research. 120(2):312-323 [DOI] 10.1161/CIRCRESAHA.116.309006. [PMID] 27799253.
2017
Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging.
Journal of the American Medical Directors Association. 18(9):810.e1-810.e4 [DOI] 10.1016/j.jamda.2017.05.018. [PMID] 28676292.
2017
Report of the National Heart, Lung, and Blood Institute Working Group on the Role of Microbiota in Blood Pressure Regulation: Current Status and Future Directions.
Hypertension (Dallas, Tex. : 1979). [DOI] 10.1161/HYPERTENSIONAHA.117.09699. [PMID] 28760940.
2017
Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon.
Frontiers in physiology. 8 [DOI] 10.3389/fphys.2017.00220. [PMID] 28446880.
2017
The Gut, Its Microbiome, and Hypertension.
Current hypertension reports. 19(4) [DOI] 10.1007/s11906-017-0734-1. [PMID] 28444579.
2016
Angiotensin II Regulation of Proliferation, Differentiation, and Engraftment of Hematopoietic Stem Cells.
Hypertension (Dallas, Tex. : 1979). 67(3):574-84 [DOI] 10.1161/HYPERTENSIONAHA.115.06474. [PMID] 26781279.
2016
Angiotensin-converting enzyme 2 inhibits high-mobility group box 1 and attenuates cardiac dysfunction post-myocardial ischemia.
Journal of molecular medicine (Berlin, Germany). 94(1):37-49 [PMID] 26498282.
2016
Anti-hypertensive Effects of Diminazene Aceturate: An Angiotensin- Converting Enzyme 2 Activator in Rats.
Protein and peptide letters. 23(1):9-16 [PMID] 26458404.
2016
Brain-Gut-Bone Marrow Axis: Implications for Hypertension and Related Therapeutics.
Circulation research. 118(8):1327-36 [DOI] 10.1161/CIRCRESAHA.116.307709. [PMID] 27081113.
2016
Hypertension-linked mechanical changes of rat gut.
Acta biomaterialia. 45:296-302 [DOI] 10.1016/j.actbio.2016.08.045. [PMID] 27567964.
2016
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.
Neuropharmacology. 105:114-123 [DOI] 10.1016/j.neuropharm.2015.12.026. [PMID] 26767952.
2016
Therapeutic potential of adipose stem cell-derived conditioned medium against pulmonary hypertension and lung fibrosis.
British journal of pharmacology. 173(19):2859-79 [DOI] 10.1111/bph.13562. [PMID] 27448286.
2015
ACE2 and Microbiota: Emerging Targets for Cardiopulmonary Disease Therapy.
Journal of cardiovascular pharmacology. 66(6):540-50 [DOI] 10.1097/FJC.0000000000000307. [PMID] 26322922.
2015
ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.
American journal of physiology. Heart and circulatory physiology. 309(10):H1697-707 [DOI] 10.1152/ajpheart.00854.2014. [PMID] 26386115.
2015
Activation of endogenous angiotensin converting enzyme 2 prevents early injuries induced by hyperglycemia in rat retina.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 48(12):1109-14 [DOI] 10.1590/1414-431X20154583. [PMID] 26421871.
2015
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice.
Vascular pharmacology. 74:103-113 [DOI] 10.1016/j.vph.2015.08.014. [PMID] 26304699.
2015
Diminazene protects corpus cavernosum against hypercholesterolemia-induced injury.
The journal of sexual medicine. 12(2):289-302 [DOI] 10.1111/jsm.12757. [PMID] 25411084.
2015
Gut dysbiosis is linked to hypertension.
Hypertension (Dallas, Tex. : 1979). 65(6):1331-40 [DOI] 10.1161/HYPERTENSIONAHA.115.05315. [PMID] 25870193.
2015
Impact of antibiotics on arterial blood pressure in a patient with resistant hypertension – A case report.
International journal of cardiology. 201:157-8 [DOI] 10.1016/j.ijcard.2015.07.078. [PMID] 26301638.
2015
Involvement of bone marrow cells and neuroinflammation in hypertension.
Circulation research. 117(2):178-91 [DOI] 10.1161/CIRCRESAHA.117.305853. [PMID] 25963715.
2015
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
British journal of pharmacology. 172(9):2219-31 [DOI] 10.1111/bph.13044. [PMID] 25522140.
2015
Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.
Antioxidants & redox signaling. 23(11):880-92 [DOI] 10.1089/ars.2014.6070. [PMID] 25867182.
2014
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979). 63(3):542-50 [DOI] 10.1161/HYPERTENSIONAHA.113.02722. [PMID] 24366083.
2014
Angiotensin II Regulates Hematopoietic Stem Cell Proliferation, Differentiation and Engraftment Efficacy
Experimental Hematology. 42(8, 1)
2014
Angiotensin II Regulates Hematopoietic Stem Cell Proliferation, Differentiation and Engraftment Efficacy
Experimental Hematology. 42(8, 1)
2014
Angiotensin-Converting Enzyme 2 Is Expressed in Corpus Cavernosum and Produces Beneficial Effects Against Hypercholesterolemia-Induced Injuries
˜The œjournal of sexual medicine (Online). 11(5, SI):240-241
2014
Direct pro-inflammatory effects of prorenin on microglia.
PloS one. 9(10) [DOI] 10.1371/journal.pone.0092937. [PMID] 25302502.
2014
Functional neural-bone marrow pathways: implications in hypertension and cardiovascular disease.
Hypertension (Dallas, Tex. : 1979). 63(6):e129-39 [DOI] 10.1161/HYPERTENSIONAHA.114.02440. [PMID] 24688127.
2014
Iba1+Microglia/Macrophages in the Rat Hypothalamic Paraventricular Nucleus Are Both Resident and Bone Marrow-Derived in Ang II Induced Hypertension
The FASEB's Journal. 28(1, S)
2014
Is natriuretic peptide receptor C a new target for hypertension therapeutics?
Hypertension (Dallas, Tex. : 1979). 63(4):661-2 [DOI] 10.1161/HYPERTENSIONAHA.113.02702. [PMID] 24470462.
2014
Neuroinflammation in pulmonary hypertension: concept, facts, and relevance.
Current hypertension reports. 16(9) [DOI] 10.1007/s11906-014-0469-1. [PMID] 25090964.
2014
Oral delivery of Angiotensin-converting enzyme 2 and Angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension.
Hypertension (Dallas, Tex. : 1979). 64(6):1248-59 [DOI] 10.1161/HYPERTENSIONAHA.114.03871. [PMID] 25225206.
2014
Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms.
PloS one. 9(4) [DOI] 10.1371/journal.pone.0093965. [PMID] 24713821.
2013
Ace2 Activation Ameliorates Endothelial Function in the Right Ventricles of Pulmonary Hypertensive Rats
The FASEB's Journal. 27
2013
Ace2 Gene Therapy Decreases Fibrosis in the Pancreas of High Fat Diet-Fed Mice
The FASEB's Journal. 27
2013
Activation of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis attenuates the cardiac reactivity to acute emotional stress.
American journal of physiology. Heart and circulatory physiology. 305(7):H1057-67 [DOI] 10.1152/ajpheart.00433.2013. [PMID] 23873801.
2013
Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors.
Diabetes. 62(4):1258-69 [DOI] 10.2337/db12-0808. [PMID] 23230080.
2013
Angiotensin Converting Enzyme-2 Activation Attenuates Right Ventricular Hypertrophy and Dysfunction After Pulmonary Artery Banding in Rats
Circulation. 128(22, S)
2013
Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3β in neuronal culture.
British journal of pharmacology. 169(4):860-74 [DOI] 10.1111/bph.12177. [PMID] 23516971.
2013
Angiotensin-converting enzyme 2 activation improves endothelial function.
Hypertension (Dallas, Tex. : 1979). 61(6):1233-8 [DOI] 10.1161/HYPERTENSIONAHA.111.00627. [PMID] 23608648.
2013
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy.
Hypertension (Dallas, Tex. : 1979). 61(3):681-9 [DOI] 10.1161/HYPERTENSIONAHA.111.00202. [PMID] 23266545.
2013
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Investigative ophthalmology & visual science. 54(6):4296-306 [DOI] 10.1167/iovs.12-11427. [PMID] 23702784.
2013
Chronic knockdown of the nucleus of the solitary tract AT1 receptors increases blood inflammatory-endothelial progenitor cell ratio and exacerbates hypertension in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979). 61(6):1328-33 [DOI] 10.1161/HYPERTENSIONAHA.111.00156. [PMID] 23547238.
2013
CNS inflammation and bone marrow neuropathy in type 1 diabetes.
The American journal of pathology. 183(5):1608-20 [DOI] 10.1016/j.ajpath.2013.07.009. [PMID] 24160325.
2013
Comparison of the transduction efficiency of tyrosine-mutant adeno-associated virus serotype vectors in kidney.
Clinical and experimental pharmacology & physiology. 40(1):53-5 [DOI] 10.1111/1440-1681.12037. [PMID] 23216315.
2013
Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology.
Hypertension (Dallas, Tex. : 1979). 62(4):746-52 [DOI] 10.1161/HYPERTENSIONAHA.113.01337. [PMID] 23959549.
2013
Diminazene aceturate improves autonomic modulation in pulmonary hypertension.
European journal of pharmacology. 713(1-3):89-93 [DOI] 10.1016/j.ejphar.2013.04.017. [PMID] 23665493.
2013
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
American journal of respiratory and critical care medicine. 187(6):648-57 [DOI] 10.1164/rccm.201205-0880OC. [PMID] 23370913.
2013
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.
Circulation research. 112(8):1104-11 [DOI] 10.1161/CIRCRESAHA.113.301077. [PMID] 23446738.
2013
Dysfunctional brain-bone marrow communication: a paradigm shift in the pathophysiology of hypertension.
Current hypertension reports. 15(4):377-89 [DOI] 10.1007/s11906-013-0361-4. [PMID] 23715920.
2013
Genetically Engineered Mesenchymal Stem Cells That Overexpress Ace2 Or Angiotensin-(1-7) Show Enhanced Nitric-Oxide Production
The FASEB's Journal. 27
2013
Lenti-Angiotensin-(1-7) Transduction of Islet Plus Cardiac Progenitor Cells Improves the Reparative Capacity in Doxorubicin Induced Cardiomyopathy
The FASEB's Journal. 27
2013
Neuroimmune communication in hypertension and obesity: a new therapeutic angle?
Pharmacology & therapeutics. 138(3):428-40 [DOI] 10.1016/j.pharmthera.2013.02.005. [PMID] 23458610.
2013
Nucleus of the solitary tract (pro)renin receptor-mediated antihypertensive effect involves nuclear factor-κB-cytokine signaling in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979). 61(3):622-7 [DOI] 10.1161/HYPERTENSIONAHA.111.199836. [PMID] 23319541.
2013
P2X7 Receptors Mediate Hormone Release in Nerve Terminals of the Neurohypophysis (Nh)
The FASEB's Journal. 27
2013
Pancreatic Ace2 Shedding Is Associated With Impaired Glycemia in High Fat Diet-Fed Mice.
The FASEB's Journal. 27
2013
Regulation of Hematopoietic Stem/Progenitor Cell Differentiation and Engraftment By Angiotensin II
Experimental Hematology. 41
2013
Role of Microglia Activation in Neurogenic Hypertension
Glia. 61
2013
SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension.
Hypertension (Dallas, Tex. : 1979). 61(5):1044-52 [DOI] 10.1161/HYPERTENSIONAHA.111.199158. [PMID] 23478097.
2013
Small Molecule Ace2 Activator, Diminazene Aceturate (Dize) Attenuates Mi-Induced Cardiac Pathophysiology
The FASEB's Journal. 27
2012
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy.
Molecular therapy : the journal of the American Society of Gene Therapy. 20(1):28-36 [DOI] 10.1038/mt.2011.155. [PMID] 21792177.
2012
Ace2 Reduces Hyperglycemia By Preventing Pancreatic Renin Angiotensin System Over-Activation in High Fat Diet-Fed Mice
The FASEB's Journal. 26
2012
Angiotensin-(1-7)/angiotensin-converting enzyme 2/mas receptor axis and related mechanisms.
International journal of hypertension. 2012 [DOI] 10.1155/2012/690785. [PMID] 22577520.
2012
Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy.
Progress in retinal and eye research. 31(5):481-94 [DOI] 10.1016/j.preteyeres.2012.04.005. [PMID] 22609081.
2012
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension.
Hypertension (Dallas, Tex. : 1979). 60(5):1316-23 [DOI] 10.1161/HYPERTENSIONAHA.112.199547. [PMID] 23045460.
2012
C1 catecholamine neurons form local circuit synaptic connections within the rostroventrolateral medulla of rat.
Neuroscience. 227:247-59 [DOI] 10.1016/j.neuroscience.2012.09.049. [PMID] 23041757.
2012
Chronic activation of endogenous angiotensin-converting enzyme 2 protects diabetic rats from cardiovascular autonomic dysfunction.
Experimental physiology. 97(6):699-709 [DOI] 10.1113/expphysiol.2011.063461. [PMID] 22286369.
2012
Dysfunctional Bone Marrow-Derived Endothelial Progenitor Cells in Chronic Ang II Infusion Rat Model of Hypertension
The FASEB's Journal. 26
2012
Effect of Dize, An Ace2 Activator On Cardiopulmonary Fibrosis and Apoptosis
Critical Care Medicine. 40
2012
Microglial-Neuronal Interactions in the Paraventricular Nucleus (Pvn): a Potential Mechanism Underlying Neurogenic Hypertension
The FASEB's Journal. 26
2012
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury.
Experimental physiology. 97(1):89-101 [DOI] 10.1113/expphysiol.2011.060673. [PMID] 21967903.
2012
New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis.
International journal of hypertension. 2012 [DOI] 10.1155/2012/147825. [PMID] 22319643.
2012
Nts (Pro)Renin Receptor (Prr)-Mediated Antihypertensive Effect Involves Nf-Kappab-Cytokine Signaling in the Spontaneously Hypertensive Rats (Shr)
The FASEB's Journal. 26
2012
Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction.
Regulatory peptides. 177(1-3):107-15 [DOI] 10.1016/j.regpep.2012.05.093. [PMID] 22595130.
2011
(Pro)Renin Receptor (Prr) Mediates Antihypertensive Effects in the Necleus of Solitary Tract (Nts) of Spontaneously Hypertensive Rats (Shr)
Hypertension. 58
2011
Ace2 Activation Improves Endothelial Function By Attenuation of Oxidative Stress
Hypertension. 58
2011
ACE2, a promising therapeutic target for pulmonary hypertension.
Current opinion in pharmacology. 11(2):150-5 [DOI] 10.1016/j.coph.2010.12.002. [PMID] 21215698.
2011
An Ace2 Activator (Dize) Improves Endothelial Progenitor Cell Function and Attenuates Pulmonary Hypertension
Hypertension. 58
2011
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases.
Experimental physiology. 96(3):287-94 [DOI] 10.1113/expphysiol.2010.055277. [PMID] 21148624.
2011
Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension.
Hypertension (Dallas, Tex. : 1979). 57(6):1026-33 [DOI] 10.1161/HYPERTENSIONAHA.111.169748. [PMID] 21536990.
2011
Cardiac Progenitor Cells (Islet-1(+)) Restore Myocardial Infarction Induced Cardiac Dysfunction and Remodeling
Hypertension. 58
2011
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
Experimental physiology. 96(10):1084-96 [DOI] 10.1113/expphysiol.2011.058578. [PMID] 21685445.
2011
Contributions of vascular inflammation in the brainstem for neurogenic hypertension.
Respiratory physiology & neurobiology. 178(3):422-8 [DOI] 10.1016/j.resp.2011.05.004. [PMID] 21601658.
2011
Dysfunctional Bone Marrow-Derived Endothelial Progenitor Cells (Epcs) in Rat Models of Neurogenic Hypertension
Hypertension. 58:E97-E98
2011
Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats.
Journal of the renin-angiotensin-aldosterone system : JRAAS. 12(4):456-61 [DOI] 10.1177/1470320311412809. [PMID] 21719524.
2011
Impaired Cd34(+) Endothelial Progenitor Cell Function in Individuals With Pulmonary Hypertension Is Restored By the Activation of Ace2/Angiotensin-(1-7)/Mas Pathway
Hypertension. 58
2011
Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology.
Experimental physiology. 96(9):863-74 [DOI] 10.1113/expphysiol.2011.056994. [PMID] 21685447.
2011
Microdissection of neural networks by conditional reporter expression from a Brainbow herpesvirus.
Proceedings of the National Academy of Sciences of the United States of America. 108(8):3377-82 [DOI] 10.1073/pnas.1015033108. [PMID] 21292985.
2011
Oral Administration of An Angiotensin-Converting Enzyme 2 Activator Improves Diabetes-Induced Cardiovascular Dysfunction
Hypertension. 58
2011
Rosa26 Angiotensin-Converting Enzyme 2 (Ace2) Knock-in Mice Exhibit Normal Cardiac Function But Attenuated Angiotensin Ii-Induced Hypertension
Hypertension. 58
2011
Stimulatory Action of the Renin-Angiotensin-Aldosterone System On the Production of Microglial Derived Cytokines
Hypertension. 58
2010
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?
Pharmacology & therapeutics. 125(1):27-38 [DOI] 10.1016/j.pharmthera.2009.07.007. [PMID] 19723538.
2010
Ace2 Activation Improves Endothelial Function
Arteriosclerosis Thrombosis and Vascular Biology. 30
2010
Ace2 Activation Improves Endothelial Function of Diabetic Rats
Hypertension. 56
2010
Ace2 Activation Improves Endothelial Function of Diabetic Rats
Hypertension. 56
2010
ACE2 activation promotes antithrombotic activity.
Molecular medicine (Cambridge, Mass.). 16(5-6):210-5 [DOI] 10.2119/molmed.2009.00160. [PMID] 20111697.
2010
Activation of the Protective Arm of Renin Angiotensin System (Ras) Corrects the Reparative Dysfunction of Diabetic Cd34+Cells
Blood. 116:1087-1088
2010
Angiotensin II Causes Imbalance Between Pro- and Anti-Inflammatory Cytokines By Modulating Gsk3 Beta in Rat Neuronal Cells
Hypertension. 56
2010
Angiotensin-Converting Enzyme 2 Activator Improves Diabetes-Induced Cardiovascular Dysfunction
Journal of Hypertension. 28:E285-E286
2010
Brain cytokines as neuromodulators in cardiovascular control.
Clinical and experimental pharmacology & physiology. 37(2):e52-7 [DOI] 10.1111/j.1440-1681.2009.05234.x. [PMID] 19566837.
2010
Brain microglial cytokines in neurogenic hypertension.
Hypertension (Dallas, Tex. : 1979). 56(2):297-303 [DOI] 10.1161/HYPERTENSIONAHA.110.150409. [PMID] 20547972.
2010
Brain-Targeted Gene Delivery of (Pro)Renin Receptor Induces Development of Hypertension in Renin Transgenic Mice
Hypertension. 56:E102-E103
2010
Diabetes-Induced Cardiovascular Dysfunction Is Improved By Angiotensin-Converting Enzyme 2 Activation: Modulation of Ace/Ang Ii/At1R and Ace2/Ang-(1-7)/Mas Receptor Axes
Hypertension. 56
2010
Exercise Training Activates Gsk3 and Increases Creb-Mediated Gene Expression in the Paraventricular Nucleus of Angiotensin-II Induced Hypertensive Rats
Hypertension. 56
2010
Involvement of the Brain (Pro) Renin Receptor in Cardiovascular Homeostasis
Hypertension. 56
2010
Involvement of the brain (pro)renin receptor in cardiovascular homeostasis.
Circulation research. 107(7):934-8 [DOI] 10.1161/CIRCRESAHA.110.226977. [PMID] 20689062.
2010
Is (pro)renin receptor a multifunctional receptor?
Hypertension (Dallas, Tex. : 1979). 55(6):1308-9 [DOI] 10.1161/HYPERTENSIONAHA.110.151142. [PMID] 20368502.
2010
Macrophage migration inhibitory factor in the paraventricular nucleus plays a major role in the sympathoexcitatory response to salt.
Hypertension (Dallas, Tex. : 1979). 56(5):956-63 [DOI] 10.1161/HYPERTENSIONAHA.110.155101. [PMID] 20937969.
2010
Neurogenic hypertension.
Experimental physiology. 95(5):569-71 [DOI] 10.1113/expphysiol.2009.047282. [PMID] 20407134.
2010
Phosphorylation of Glycogen Synthase Kinase 3 Beta (Gsk3 Beta) Contributes To the Development of Pulmonary Hypertension
Hypertension. 56
2010
Spectral imaging reveals microvessel physiology and function from anastomoses to thromboses.
Journal of biomedical optics. 15(1) [DOI] 10.1117/1.3316299. [PMID] 20210437.
2010
Targeting the vasoprotective axis of the renin-angiotensin system: a novel strategic approach to pulmonary hypertensive therapy.
Current hypertension reports. 12(4):212-9 [DOI] 10.1007/s11906-010-0122-6. [PMID] 20556668.
2010
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension.
American journal of respiratory and critical care medicine. 182(8):1065-72 [DOI] 10.1164/rccm.200912-1840OC. [PMID] 20581171.
2010
Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases.
Hypertension (Dallas, Tex. : 1979). 55(2):207-13 [DOI] 10.1161/HYPERTENSIONAHA.109.140145. [PMID] 20038757.
2010
Xnt, a Synthetic Ace2 Activator, Improves Endothelial Function
Journal of Hypertension. 28
2009
Aav-Mediated Increases in (Pro)Renin Receptor Expression in the Supraoptic Nucleus Regulate Vasopressin Secretion and Body Fluid Homeostasis
Hypertension. 54
2009
Ace2 Activation Exerts Antithrombotic Activity
. 40
2009
Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats.
Circulation research. 104(12):1421-8 [DOI] 10.1161/CIRCRESAHA.108.192302. [PMID] 19443838.
2009
Cardiac Ace2 Activation Protects the Heart Against Hypertension-Induced Fibrosis Involving Erk
Hypertension. 54:E111-E112
2009
Central Activation of the Ace2-Ang-(1-7)-Mas Axis Markedly Reduces the Tachycardia Evoked By Acute Stress Exposure
Hypertension. 54
2009
Chronic blockade of phosphatidylinositol 3-kinase in the nucleus tractus solitarii is prohypertensive in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979). 53(1):97-103 [DOI] 10.1161/HYPERTENSIONAHA.108.122341. [PMID] 19015400.
2009
Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.
American journal of respiratory and critical care medicine. 179(11):1048-54 [DOI] 10.1164/rccm.200811-1678OC. [PMID] 19246717.
2009
Increased Expression of Ndufa10, a Subunit of Mitochondrial Complex 1, in the Cardiovascular Relevant Brain Regions of the Spontaneously Hypertensive Rat
Hypertension. 54
2009
Interleukin-10 in the Hypothalamic Paraventricular Nucleus Attenuates the Pressor Response To Angiotensin II
Hypertension. 54
2009
New Targets in Pulmonary Hypertension-Another Ace Up the Sleeve
American Journal of Respiratory and Critical Care Medicine. 180
2009
Phosphate-activated glutaminase-containing neurons in the rat paraventricular nucleus express angiotensin type 1 receptors.
Hypertension (Dallas, Tex. : 1979). 54(4):845-51 [DOI] 10.1161/HYPERTENSIONAHA.109.134684. [PMID] 19667250.
2009
Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.
Hypertension (Dallas, Tex. : 1979). 54(2):365-71 [DOI] 10.1161/HYPERTENSIONAHA.108.125468. [PMID] 19564552.
2009
Prorenin Receptor (Prr) Immunoreactivity (Ir) in Cardiovascular (Cv) Regulatory Brain Nuclei Is Exclusive To Neurons and Colocalized With the Angiotensin (Ang) II Type 1 Receptor (At1R)
Hypertension. 54
2009
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia.
The Journal of clinical investigation. 119(11):3487-96 [DOI] 10.1172/JCI39482. [PMID] 19805914.
2009
Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat.
Circulation research. 105(12):1248-55 [DOI] 10.1161/CIRCRESAHA.109.208926. [PMID] 19850939.
2008
Aav-Mediated Gene Transfer of Ace2 Protects Retinal Vascular Dysfunction in An Animal Model of Diabetic Retinopathy
Journal of Hypertension. 26
2008
Ace2 Activation Attenuates Monocrotatine-Induced Pulmonary Hypertension in Rats
Journal of Hypertension. 26
2008
Ace2 Activation Prevents Monocrotaline-Induced Pulmonary Hypertension
Hypertension. 52
2008
Aminopeptidase A: could it be a novel target for neurogenic hypertension?
Hypertension (Dallas, Tex. : 1979). 51(5):1273-4 [DOI] 10.1161/HYPERTENSIONAHA.107.109561. [PMID] 18362227.
2008
Angiotensin-(1-7) as An Antihypertensive, Antifibrotic Target
Current Hypertension Reports. 10(9):227-232 [DOI] 10.1007/s11906-008-0043-9. [PMID] 21615360.
2008
Angiotensin-(1-7) as an antihypertensive, antifibrotic target.
Current hypertension reports. 10(3):227-32 [PMID] 18765095.
2008
Are we poised to target ACE2 for the next generation of antihypertensives?
Journal of molecular medicine (Berlin, Germany). 86(6):685-90 [DOI] 10.1007/s00109-008-0339-x. [PMID] 18449520.
2008
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979). 52(2):351-8 [DOI] 10.1161/HYPERTENSIONAHA.108.114371. [PMID] 18606900.
2008
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology.
Hypertension (Dallas, Tex. : 1979). 51(3):712-8 [DOI] 10.1161/HYPERTENSIONAHA.107.100693. [PMID] 18250366.
2008
Cardiovascular protection by angiotensin-converting enzyme 2: a new paradigm.
Future cardiology. 4(2):175-82 [DOI] 10.2217/14796678.4.2.175. [PMID] 19804294.
2008
Characterization of a functional (pro)renin receptor in rat brain neurons.
Experimental physiology. 93(5):701-8 [DOI] 10.1113/expphysiol.2008.041988. [PMID] 18326551.
2008
Characterization of the Rostral Vetrolateral Medulla (Rvlm) Neurons From Adult Rat Brain in Primary Culture
Journal of Hypertension. 26
2008
Differential regulation of the renin-angiotensin system by nicotine in WKY and SHR glia.
Journal of molecular neuroscience : MN. 35(2):151-60 [DOI] 10.1007/s12031-007-9025-7. [PMID] 18369742.
2008
Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice.
Molecular therapy : the journal of the American Society of Gene Therapy. 16(10):1688-94 [DOI] 10.1038/mt.2008.164. [PMID] 18665154.
2008
Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.
Circulation. 118(7):722-30 [DOI] 10.1161/CIRCULATIONAHA.107.736801. [PMID] 18663089.
2008
Genomic and proteomic approaches for targeting of angiotensin-converting enzyme2 for cardiovascular diseases.
Current opinion in cardiology. 23(4):364-9 [DOI] 10.1097/HCO.0b013e328303b79b. [PMID] 18520721.
2008
Glutamatergic Neurons in Adult Rat Paraventricular Nucleus Contain Functional Angiotensin Type 1 Receptors
Hypertension. 52
2008
Increased Expression of (Pro) Renin Receptor in Primary Neuronal Cultures From the Spontaneously Hypertensive Rat Brain
Hypertension. 52
2008
Mas-Independent Vasorelaxant Actions of Ala(1)-Angiotensin-(1-7), a Novel Ace2 Product
Hypertension. 52:E52-E53
2008
Overexpression of Ace 2 in the Nucleus Tractus Solitarius Improves Baroreflex Function in the Spontaneously Hypertensive Rat
Journal of Hypertension. 26
2008
Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects.
Circulation research. 103(6):580-90 [DOI] 10.1161/CIRCRESAHA.108.171835. [PMID] 18689573.
2008
Prevention of Monocrotaline-Induced Pulmonary Hypertension By Lenti-Viral Mediated Gene Delivery of Angiotensin-(1-7)
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2008
Recent advances in the renin-angiotensin system: angiotensin-converting enzyme 2 and (pro)renin receptor.
Experimental physiology. 93(5):517-8 [DOI] 10.1113/expphysiol.2008.042861. [PMID] 18448661.
2008
Rvlm Neurons From the Adult Rat Brain Maintain in Vivo Physiological Properties in Primary Culture
Hypertension. 52
2008
Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.
Hypertension (Dallas, Tex. : 1979). 51(5):1312-7 [DOI] 10.1161/HYPERTENSIONAHA.107.108944. [PMID] 18391097.
2008
Tnf-Alpha-Induced Oxidative Stress Upregulates Components of Renin-Angiotensin System in the Heart
Hypertension. 52
2007
ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts.
Clinical science (London, England : 1979). 113(8):357-64 [PMID] 17600530.
2007
ACE2: a new target for cardiovascular disease therapeutics.
Journal of cardiovascular pharmacology. 50(2):112-9 [PMID] 17703127.
2007
Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension.
Current hypertension reports. 9(3):228-35 [PMID] 17519130.
2007
Lack of macrophage migration inhibitory factor regulation is linked to the increased chronotropic action of angiotensin II in SHR neurons.
Hypertension (Dallas, Tex. : 1979). 49(3):528-34 [PMID] 17261648.
2007
Nicotine modulates the renin-angiotensin system of cultured neurons and glial cells from cardiovascular brain areas of Wistar Kyoto and spontaneously hypertensive rats.
Journal of molecular neuroscience : MN. 33(3):284-93 [PMID] 17952638.
2007
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979). 49(4):926-31 [PMID] 17325232.
2007
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
American journal of physiology. Heart and circulatory physiology. 292(2):H727-35 [PMID] 17085538.
2007
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7).
American journal of physiology. Heart and circulatory physiology. 292(2):H736-42 [PMID] 17098828.
2006
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.
Physiological genomics. 27(1):12-9 [PMID] 16788004.
2006
ACE2: A novel therapeutic target for cardiovascular diseases.
Progress in biophysics and molecular biology. 91(1-2):163-98 [PMID] 16009403.
2006
Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation.
The Journal of comparative neurology. 499(5):840-59 [PMID] 17048222.
2006
Macrophage migration inhibitory factor in the PVN attenuates the central pressor and dipsogenic actions of angiotensin II.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(10):1748-50 [PMID] 16809436.
2006
Potential of gene therapy strategy for the treatment of hypertension.
Hypertension (Dallas, Tex. : 1979). 47(1):6-9 [PMID] 16344374.
2005
Adenoviral-mediated neuron specific transduction of angiotensin II type 2 receptors.
Regulatory peptides. 126(3):213-22 [PMID] 15664669.
2005
Angiotensin II type 2 receptor-mediated gene expression profiling in human coronary artery endothelial cells.
Hypertension (Dallas, Tex. : 1979). 45(4):692-7 [PMID] 15710780.
2005
Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertension.
Experimental physiology. 90(3):299-305 [PMID] 15640278.
2005
Effects of early perturbation of the renin-angiotensin system on cardiovascular remodeling in spontaneously hypertensive rats.
Vascular pharmacology. 42(3):93-8 [PMID] 15792926.
2005
Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat.
Circulation research. 96(3):277-9 [PMID] 15662030.
2005
Intronic enhancement of angiotensin II type 2 receptor transgene expression in vitro and in vivo.
Biochemical and biophysical research communications. 336(1):29-35 [PMID] 16122703.
2005
NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II.
Circulation research. 96(6):659-66 [PMID] 15746442.
2005
Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(6):626-8 [PMID] 15659536.
2005
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.
Experimental physiology. 90(5):783-90 [PMID] 16049057.
2005
Selective silencing of angiotensin receptor subtype 1a (AT1aR) by RNA interference.
Hypertension (Dallas, Tex. : 1979). 45(1):115-9 [PMID] 15569855.
2004
Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension.
Physiological genomics. 19(3):255-61 [PMID] 15383639.
2004
Cloning and characterization of a secreted form of angiotensin-converting enzyme 2.
Regulatory peptides. 122(2):61-7 [PMID] 15380922.
2004
Decrease in hypothalamic gamma adducin in rat models of hypertension.
Hypertension (Dallas, Tex. : 1979). 43(2):324-8 [PMID] 14732736.
2004
Elevated blood pressure in normotensive rats produced by ‘knockdown’ of the angiotensin type 2 receptor.
Experimental physiology. 89(3):313-22 [PMID] 15123567.
2004
Functional genomics as an emerging strategy for the investigation of central mechanisms in experimental hypertension.
Progress in biophysics and molecular biology. 84(2-3):107-23 [PMID] 14769432.
2004
Macrophage migration inhibitory factor: an intracellular inhibitor of angiotensin II-induced increases in neuronal activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(44):9944-52 [PMID] 15525779.
2004
Prevention of cardiac hypertrophy by angiotensin II type-2 receptor gene transfer.
Hypertension (Dallas, Tex. : 1979). 43(6):1233-8 [PMID] 15166182.
2004
Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor.
Hypertension (Dallas, Tex. : 1979). 44(6):903-6 [PMID] 15492138.
2003
Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives.
British journal of pharmacology. 139(2):191-202 [PMID] 12770924.
2003
Desflurane and sevoflurane attenuate oxygen and glucose deprivation-induced neuronal cell death.
Journal of neurosurgical anesthesiology. 15(3):193-9 [PMID] 12826966.
2003
Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo.
Physiological genomics. 12(3):221-8 [PMID] 12488511.
2003
Endothelial-independent prevention of high blood pressure in L-NAME-treated rats by angiotensin II type I receptor antisense gene therapy.
Experimental physiology. 88(4):467-73 [PMID] 12861333.
2003
Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells.
Biochemical and biophysical research communications. 310(3):710-4 [PMID] 14550259.
2003
PI3-kinase inhibitors abolish the enhanced chronotropic effects of angiotensin II in spontaneously hypertensive rat brain neurons.
Journal of neurophysiology. 90(5):3155-60 [PMID] 12904331.
2003
Transduction of a functional domain of the AT1 receptor in neurons by HIV-Tat PTD.
Hypertension (Dallas, Tex. : 1979). 41(3 Pt 2):751-6 [PMID] 12623991.
2002
ANG II stimulation of neuritogenesis involves protein kinase B in brain neurons.
American journal of physiology. Regulatory, integrative and comparative physiology. 283(1):R107-14 [PMID] 12069936.
2002
Angiotensin II and IV stimulate expression and release of plasminogen activator inhibitor-1 in cultured human coronary artery endothelial cells.
Journal of cardiovascular pharmacology. 39(6):789-94 [PMID] 12021572.
2002
Blood pressure-independent attenuation of cardiac hypertrophy by AT(1)R-AS gene therapy.
Hypertension (Dallas, Tex. : 1979). 39(5):969-75 [PMID] 12019278.
2002
Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII.
Hypertension (Dallas, Tex. : 1979). 39(2 Pt 2):562-6 [PMID] 11882608.
2002
Genetic targeting of the renin-angiotensin system for long-term control of hypertension.
Current hypertension reports. 4(1):25-31 [PMID] 11790288.
2002
Hypertension-linked decrease in the expression of brain gamma-adducin.
Circulation research. 91(7):633-9 [PMID] 12364392.
2002
Large-scale production of retroviral vectors for systemic gene delivery.
Methods in enzymology. 346:562-73 [PMID] 11883091.
2002
Obligatory role of protein kinase Cbeta and MARCKS in vesicular trafficking in living neurons.
Hypertension (Dallas, Tex. : 1979). 39(2 Pt 2):567-72 [PMID] 11882609.
2001
ANG II-mediated inhibition of neuronal delayed rectifier K+ current: role of protein kinase C-alpha.
American journal of physiology. Cell physiology. 281(1):C17-23 [PMID] 11401823.
2001
Angiotensin II increases vesicular trafficking in brain neurons.
Hypertension (Dallas, Tex. : 1979). 37(2 Pt 2):677-82 [PMID] 11230355.
2001
Characterization of signal transduction pathway in neurotropic action of angiotensin II in brain neurons.
Endocrinology. 142(8):3502-11 [PMID] 11459796.
2001
Gene expression profiling of rat brain neurons reveals angiotensin II-induced regulation of calmodulin and synapsin I: possible role in neuromodulation.
Endocrinology. 142(3):1009-16 [PMID] 11181513.
2001
Gene therapy attenuates the elevated blood pressure and glucose intolerance in an insulin-resistant model of hypertension.
Journal of hypertension. 19(9):1553-8 [PMID] 11564974.
2001
Gene therapy for cardiovascular disorders: is there a future?
Annals of the New York Academy of Sciences. 953:31-42 [PMID] 11795421.
2001
Gene therapy in cardiovascular disease. Current status.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. 1(1):55-66 [PMID] 12173315.
2001
Gene therapy to control hypertension: current studies and future perspectives.
The American journal of the medical sciences. 322(1):1-6 [PMID] 11465240.
2001
Genetic targeting for cardiovascular therapeutics: are we near the summit or just beginning the climb?
Physiological genomics. 7(2):79-94 [PMID] 11773594.
2001
Novel role of macrophage migration inhibitory factor in angiotensin II regulation of neuromodulation in rat brain.
Endocrinology. 142(11):4623-30 [PMID] 11606427.
2001
Oxygen and glucose deprivation-induced neuronal apoptosis is attenuated by halothane and isoflurane.
Anesthesia and analgesia. 93(5):1281-7 [PMID] 11682415.
2001
Systemic Delivery of aTransgene in Intact Animals by a Retroviral Vector.
Methods in molecular medicine. 51:67-81 [DOI] 10.1385/1-59259-087-X:67. [PMID] 21331710.
2001
The future of hypertension therapy: sense, antisense, or nonsense?
Hypertension (Dallas, Tex. : 1979). 37(2 Pt 2):357-64 [PMID] 11230300.
2000
Angiotensin I-converting enzyme antisense gene therapy causes permanent antihypertensive effects in the SHR.
Hypertension (Dallas, Tex. : 1979). 35(1 Pt 2):202-8 [PMID] 10642298.
2000
Angiotensin I-converting enzyme antisense prevents altered renal vascular reactivity, but not high blood pressure, in spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979). 35(1 Pt 2):209-13 [PMID] 10642299.
2000
Attenuation of hypertension by systemic delivery of retroviral vector containing type I angiotensin II receptor antisense cDNA.
Methods (San Diego, Calif.). 22(3):211-8 [PMID] 11071816.
2000
Current perspectives on the use of gene therapy for hypertension.
Circulation research. 87(12):1118-22 [PMID] 11110768.
2000
Gene therapy for hypertension and restenosis.
Journal of the renin-angiotensin-aldosterone system : JRAAS. 1(3):211-6 [PMID] 11881028.
2000
Inability to induce hypertension in normotensive rat expressing AT(1) receptor antisense.
Circulation research. 86(11):1167-72 [PMID] 10850969.
2000
Retrovirally mediated delivery of angiotensin II type 1 receptor antisense in vitro and in vivo.
Methods in enzymology. 314:581-90 [PMID] 10565039.
2000
Targeting of the renin-angiotensin system by antisense gene therapy: a possible strategy for the long-term control of hypertension.
Journal of hypertension. 18(4):353-62 [PMID] 10779083.
2000
The angiotensin II type 2 receptor: an enigma with multiple variations.
American journal of physiology. Endocrinology and metabolism. 278(3):E357-74 [PMID] 10710489.
1999
Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension.
Hypertension (Dallas, Tex. : 1979). 33(1 Pt 2):360-5 [PMID] 9931130.
1999
Angiotensin II type 1 receptor-modulated signaling pathways in neurons.
Molecular neurobiology. 19(1):25-41 [PMID] 10321970.
1999
Increased expression of calreticulin is linked to ANG IV-mediated activation of lung endothelial NOS.
The American journal of physiology. 277(4):L794-801 [DOI] 10.1152/ajplung.1999.277.4.L794. [PMID] 10516221.
1999
Is antisense gene therapy a step in the right direction in the control of hypertension?
The American journal of physiology. 277(2):H423-32 [DOI] 10.1152/ajpheart.1999.277.2.H423. [PMID] 10444465.
1999
Permanent cardiovascular protection from hypertension by the AT(1) receptor antisense gene therapy in hypertensive rat offspring.
Circulation research. 85(10):e44-50 [PMID] 10559146.
1999
Regulation of brain glucose transporters by glucose and oxygen deprivation.
Metabolism: clinical and experimental. 48(4):422-31 [PMID] 10206432.
1999
Reversal of hypertension by angiotensin II type 1 receptor antisense gene therapy in the adult SHR.
The American journal of physiology. 277(3):H1260-4 [DOI] 10.1152/ajpheart.1999.277.3.H1260. [PMID] 10484448.
1999
Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(7):2413-23 [PMID] 10087056.
1999
Sustained inhibition of angiotensin I-converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA.
Circulation research. 85(7):614-22 [PMID] 10506486.
1999
The potential use of gene therapy in the control of hypertension.
Drugs of today (Barcelona, Spain : 1998). 35(12):925-30 [PMID] 12973419.
1998
Angiotensin II-induced nuclear targeting of the angiotensin type 1 (AT1) receptor in brain neurons.
Endocrinology. 139(1):365-75 [PMID] 9421435.
1998
Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation.
The American journal of physiology. 275(6):L1061-8 [DOI] 10.1152/ajplung.1998.275.6.L1061. [PMID] 9843842.
1998
Angiotensin receptors and norepinephrine neuromodulation: implications of functional coupling.
Regulatory peptides. 73(3):141-7 [PMID] 9556076.
1998
AT1 receptor-mediated nuclear translocation of Raf-1 in brain neurons.
Journal of neurochemistry. 70(1):424-7 [PMID] 9422390.
1998
Attenuation of ANG II actions by adenovirus delivery of AT1 receptor antisense in neurons and SMC.
The American journal of physiology. 274(2):H719-27 [DOI] 10.1152/ajpheart.1998.274.2.H719. [PMID] 9486279.
1998
Involvement of p62 nucleoporin in angiotensin II-induced nuclear translocation of STAT3 in brain neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 18(4):1329-36 [PMID] 9454842.
1998
MAP kinase-independent signaling in angiotensin II regulation of neuromodulation in SHR neurons.
Hypertension (Dallas, Tex. : 1979). 32(3):473-81 [PMID] 9740613.
1998
Molecular cloning of the cDNA coding sequence of IL-2 receptor-gamma (gammac) from human and murine forebrain: expression in the hippocampus in situ and by brain cells in vitro.
Brain research. Molecular brain research. 53(1-2):152-62 [PMID] 9473647.
1998
Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy.
Proceedings of the National Academy of Sciences of the United States of America. 95(5):2664-9 [PMID] 9482944.
1998
Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons.
The Journal of cell biology. 142(1):217-27 [PMID] 9660875.
1997
Angiotensin II-induced phosphorylation of the AT1 receptor from rat brain neurons.
Hypertension (Dallas, Tex. : 1979). 30(3 Pt 1):351-7 [PMID] 9314416.
1997
Angiotensin receptors and norepinephrine neuromodulation: implications of functional coupling.
Regulatory peptides. 72(2-3):139-45 [PMID] 9652973.
1997
Functional interactions between neuronal AT1 and AT2 receptors.
Endocrinology. 138(5):2195-8 [PMID] 9112419.
1997
Identification of a system N-like Na(+)-dependent glutamine transport activity in rat brain neurons.
Journal of neurochemistry. 68(3):954-60 [PMID] 9048740.
1997
Intracellular staining of angiotensin receptors in the PVN and SON of the rat.
Brain research. 754(1-2):307-10 [PMID] 9134989.
1997
Involvement of MAP kinase in angiotensin II-induced phosphorylation and intracellular targeting of neuronal AT1 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 17(5):1660-9 [PMID] 9030625.
1997
Losartan versus gene therapy: chronic control of high blood pressure in spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979). 30(3 Pt 1):363-70 [PMID] 9314418.
1996
Angiotensin II regulation of neuromodulation: downstream signaling mechanism from activation of mitogen-activated protein kinase.
The Journal of cell biology. 135(6 Pt 1):1609-17 [PMID] 8978826.
1996
Angiotensin II regulation of plasminogen activator inhibitor-1 gene expression in neurons of normotensive and spontaneously hypertensive rat brains.
Endocrinology. 137(6):2503-13 [PMID] 8641204.
1996
Angiotensin II regulation of tyrosine hydroxylase gene expression in the neuronal cultures of normotensive and spontaneously hypertensive rats.
Endocrinology. 137(8):3566-76 [PMID] 8754788.
1996
AT1 receptor density changes during development of hypertension in hyperinsulinemic rats.
Clinical and experimental hypertension (New York, N.Y. : 1993). 18(6):793-810 [PMID] 8842564.
1996
AT1-receptors and cellular actions of angiotensin II in neuronal cultures of stroke prone-spontaneously hypertensive rat brain.
Advances in experimental medicine and biology. 396:71-8 [PMID] 8726687.
1996
Changes in angiotensin AT1 receptor density during hypertension in fructose-fed rats.
Advances in experimental medicine and biology. 396:49-58 [PMID] 8726685.
1996
Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense.
Proceedings of the National Academy of Sciences of the United States of America. 93(18):9960-5 [PMID] 8790439.
1996
Induced nitric oxide synthesis is dependent on induced alternatively spliced CAT-2 encoding L-arginine transport in brain astrocytes.
The Journal of biological chemistry. 271(39):24017-22 [PMID] 8798637.
1996
Lack of cross talk between alpha1-adrenergic and angiotensin type 1 receptors in neurons of spontaneously hypertensive rat brain.
Hypertension (Dallas, Tex. : 1979). 27(6):1277-83 [PMID] 8641736.
1996
Regulation of neuromodulatory actions of angiotensin II in the brain neurons by the Ras-dependent mitogen-activated protein kinase pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(13):4047-58 [PMID] 8753867.
1996
Regulation of norepinephrine transport system by angiotensin II in neuronal cultures of normotensive and spontaneously hypertensive rat brains.
Endocrinology. 137(2):763-72 [PMID] 8593828.
1996
Regulation of the manganese superoxide dismutase and inducible nitric oxide synthase gene in rat neuronal and glial cells.
Journal of neurochemistry. 66(5):2128-35 [PMID] 8780045.
1995
Angiotensin II increases glucose uptake and glucose transporter-1 mRNA levels in astroglia.
The American journal of physiology. 268(3 Pt 1):E384-90 [PMID] 7900784.
1995
AT1 receptors and angiotensin actions in the brain and neuronal cultures of normotensive and hypertensive rats.
Advances in experimental medicine and biology. 377:331-48 [PMID] 7484436.
1995
Delivery of angiotensin II type 1 receptor antisense inhibits angiotensin action in neurons from hypertensive rat brain.
Proceedings of the National Academy of Sciences of the United States of America. 92(7):2914-8 [PMID] 7708748.
1995
Retrovirus-mediated transfer of an angiotensin type I receptor (AT1-R) antisense sequence decreases AT1-Rs and angiotensin II action in astroglial and neuronal cells in primary cultures from the brain.
Proceedings of the National Academy of Sciences of the United States of America. 92(4):1162-6 [PMID] 7862653.
1994
Growth factor-induced neurite growth in primary neuronal cultures of dogs with neuronal ceroid lipofuscinosis.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 12(3):185-96 [PMID] 7942092.
1994
Interactions of glucocorticoids and cyclic AMP in the tissue-specific regulation of angiotensinogen.
Kidney international. 46(6):1574-6 [PMID] 7700010.
1994
Peptide receptors in astroglia: focus on angiotensin II and atrial natriuretic peptide.
Glia. 11(2):110-6 [PMID] 7927641.
1994
Receptor-mediated effects of angiotensin II on neurons.
Frontiers in neuroendocrinology. 15(3):203-30 [PMID] 7859913.
1994
Regulation of angiotensin II type 1 receptor mRNA in neuronal cultures of normotensive and spontaneously hypertensive rat brains by phorbol esters and forskolin.
Journal of neurochemistry. 62(6):2079-84 [PMID] 8189216.
1993
Angiotensin II type 1 receptor mRNA levels in the brains of normotensive and spontaneously hypertensive rats.
Journal of neurochemistry. 60(5):1949-52 [PMID] 8473909.
1993
Angiotensin II type 1 receptor-mediated stimulation of c-fos gene expression in astroglial cultures.
The American journal of physiology. 265(4 Pt 1):C1046-9 [PMID] 8238298.
1993
Angiotensin II type 2 receptor expression in neuronal cultures from spontaneously hypertensive rat brain.
Regulatory peptides. 44(2):181-8 [PMID] 8385790.
1993
Immunohistochemical mapping of angiotensin AT1 receptors in the brain.
Regulatory peptides. 44(2):95-107 [PMID] 8469778.
1993
Increased angiotensin II type-1 receptor gene expression in neuronal cultures from spontaneously hypertensive rats.
Endocrinology. 132(4):1715-22 [PMID] 8462471.
1993
Inhibition of central angiotensin responses by angiotensin type-1 receptor antibody.
Hypertension (Dallas, Tex. : 1979). 21(6 Pt 2):1062-5 [PMID] 8505093.
1993
Insulin receptor-related receptor: an orphan with neurotrophic/neuromodulatory potential.
Endocrinology. 133(1):1-2 [PMID] 8100517.
1993
Insulin stimulates phosphatidylinositol 3-kinase activity in rat neuronal primary cultures.
Journal of neurochemistry. 61(1):360-3 [PMID] 8390565.
1993
Insulin-like growth factor I receptors and IGF-I actions in neuronal cultures from the brain.
Annals of the New York Academy of Sciences. 692:89-101 [PMID] 7692799.
1993
The cellular and physiological actions of insulin in the central nervous system.
Neurochemistry international. 22(1):1-10 [PMID] 8443563.
1992
Angiotensin II stimulation of plasminogen activator inhibitor-1 gene expression in astroglial cells from the brain.
Endocrinology. 130(3):1255-62 [PMID] 1537291.
1992
Angiotensin-II induction of plasminogen activator inhibitor-1 gene expression in astroglial cells of normotensive and spontaneously hypertensive rat brain.
Molecular endocrinology (Baltimore, Md.). 6(12):2009-17 [PMID] 1491687.
1992
Characterization of a polyclonal anti-peptide antibody to the angiotensin II type-1 (AT1) receptor.
Biochemical and biophysical research communications. 183(2):781-8 [PMID] 1550583.
1992
Insulin-like growth factor I receptor binding in brains of Alzheimer’s and alcoholic patients.
Journal of neurochemistry. 58(4):1205-10 [PMID] 1312569.
1991
Angiotensin II induces secretion of plasminogen activator inhibitor 1 and a tissue metalloprotease inhibitor-related protein from rat brain astrocytes.
Proceedings of the National Academy of Sciences of the United States of America. 88(5):1928-32 [PMID] 2000398.
1991
Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain.
Proceedings of the National Academy of Sciences of the United States of America. 88(17):7567-71 [PMID] 1881896.
1991
Binding of [125I]-insulin-like growth factor-1 (IGF-1) in brains of Alzheimer’s and alcoholic patients.
Advances in experimental medicine and biology. 293:483-92 [PMID] 1662868.
1991
Developmental expression of rat insulin-like growth factor binding protein-2 by astrocytic glial cells in culture.
Endocrinology. 129(2):1066-74 [PMID] 1713158.
1991
Developmental regulation of insulin-like growth factor-I-stimulated glucose transporter in rat brain astrocytes.
Endocrinology. 128(5):2548-57 [PMID] 1850355.
1991
Glucose transporters in central nervous system glucose homeostasis.
Advances in experimental medicine and biology. 293:397-404 [PMID] 1767739.
1991
Insulin-like growth factor I (IGF-I) receptors and IGF-I action in oligodendrocytes from rat brains.
Regulatory peptides. 33(2):117-31 [PMID] 1652776.
1991
Insulin-like growth factor I: a possible modulator of intercellular communication in the brain.
Advances in experimental medicine and biology. 293:493-505 [PMID] 1722624.
1990
Alpha 1-adrenergic receptors in the brain: characterization in astrocytic glial cultures and comparison with neuronal cultures.
Brain research. 527(2):318-25 [PMID] 1979238.
1990
Alpha-1-adrenergic receptors in the nucleus tractus solitarii region of rats with experimental and genetic hypertension.
Brain research. 519(1-2):261-5 [PMID] 1975764.
1990
Effects of phorbol ester on immunoreactive protein kinase C, insulin binding, and glucose uptake in astrocytic glial and neuronal cells from the brain.
Neurochemical research. 15(3):273-8 [PMID] 2195375.
1990
Immunoreactive atrial natriuretic peptide in neuronal and glial cells of spontaneously hypertensive rat brain.
The American journal of physiology. 258(1 Pt 1):C109-14 [PMID] 2137292.
1990
Phorbol esters increase insulin binding in astrocytic glial but not neuronal cells in primary culture from the brain.
Brain research. 521(1-2):192-6 [PMID] 2207658.
1990
Physiological and pharmacological comparisons of angiotensin II receptors in neuronal and astrocyte glial cultures.
Progress in neurobiology. 34(5):355-85 [PMID] 2192392.
1990
Regulation of rat brain/HepG2 glucose transporter gene expression by phorbol esters in primary cultures of neuronal and astrocytic glial cells.
Endocrinology. 126(1):545-9 [PMID] 2294004.
1990
The influence of angiotensin II on catecholamine synthesis in neuronal cultures from rat brain.
Biochemical and biophysical research communications. 167(2):492-7 [PMID] 2322238.
1989
Alpha 2-adrenergic receptors in neuronal and glial cultures: characterization and comparison.
Journal of neurochemistry. 53(1):287-96 [PMID] 2542464.
1989
Angiotensin receptors in pulmonary arterial and aortic endothelial cells.
The American journal of physiology. 256(5 Pt 1):C987-93 [PMID] 2719100.
1989
Characterization of epidermal growth factor receptors in astrocytic glial and neuronal cells in primary culture.
Endocrinology. 124(1):240-7 [PMID] 2783308.
1989
Chromatographic methods for characterization of angiotensin in brain tissue.
Methods in enzymology. 168:545-66 [PMID] 2725311.
1989
Effects of phorbol esters and a calcium ionophore on angiotensin II binding in rat brain synaptosomes.
Neurochemical research. 14(1):25-30 [PMID] 2496327.
1989
Insulin and IGF-I stimulate phosphorylation of their respective receptors in intact neuronal and glial cells in primary culture.
Journal of molecular neuroscience : MN. 1(1):3-8 [PMID] 2561992.
1989
Insulin and insulin-like growth factor receptors in the nervous system.
Molecular neurobiology. 3(1-2):71-100 [PMID] 2553069.
1989
Lack of alpha-1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures from spontaneously hypertensive rat brain.
Molecular and cellular biochemistry. 91(1-2):111-5 [PMID] 2560138.
1989
Metabolism of angiotensin peptides by neuronal and glial cultures from rat brain.
Journal of neurochemistry. 52(3):863-8 [PMID] 2537380.
1989
Regulation of rat brain/HepG2 glucose transporter gene expression by insulin and insulin-like growth factor-I in primary cultures of neuronal and glial cells.
Endocrinology. 125(1):314-20 [PMID] 2661208.
1989
Release of immunoreactive angiotensin II from neuronal cultures: adrenergic influences.
The American journal of physiology. 257(3 Pt 1):C588-95 [PMID] 2571298.
1988
Alpha 1-adrenergic receptor stimulated responses.
Journal of cardiovascular pharmacology. 11 Suppl 1:S99-106 [PMID] 2459524.
1988
Angiotensinogen gene expression in neuronal and glial cells in primary cultures of rat brain.
Journal of neuroscience research. 19(3):287-90 [PMID] 3379645.
1988
Biosynthesis of angiotensinogen and angiotensins by brain cells in primary culture.
Journal of neurochemistry. 51(2):398-405 [PMID] 3392535.
1988
Development of brain insulin receptors.
The International journal of biochemistry. 20(3):225-30 [PMID] 3281864.
1988
Dexamethasone reduces steady state insulin-like growth factor I messenger ribonucleic acid levels in rat neuronal and glial cells in primary culture.
Endocrinology. 123(5):2565-70 [PMID] 2458916.
1988
Effect of nitrogen dioxide on surface membrane fluidity and insulin receptor binding of pulmonary endothelial cells.
Biochemical pharmacology. 37(8):1497-507 [PMID] 3358780.
1988
Effects of beta-naphthoflavone on insulin receptor binding and protein kinase activity in rat liver and placenta.
Molecular pharmacology. 33(3):250-6 [PMID] 2832720.
1988
Immunocytochemical and biochemical characterization of angiotensin I and II in cultured neuronal and glial cells from rat brain.
Neuroendocrinology. 47(2):125-32 [PMID] 3344064.
1988
Increased expression of alpha 1-adrenergic receptors in the hypothalamus of spontaneously hypertensive rats.
Brain research. 439(1-2):187-94 [PMID] 2833983.
1988
Insulin and related growth factors: effects on the nervous system and mechanism for neurite growth and regeneration. Understanding brain development and repair of cns injury.
Neurochemistry international. 12(4):415-7 [PMID] 20501245.
1988
Insulin receptors in the brain: structural and physiological characterization.
Neurochemical research. 13(4):297-303 [PMID] 3292965.
1988
Interaction of calcium with receptor-stimulated phosphoinositide hydrolysis in brain and liver.
Annals of the New York Academy of Sciences. 522:88-95 [PMID] 2837125.
1988
Pharmacological characterization of high affinity choline transporters in primary neuronal cultures in rat brain.
Neuropharmacology. 27(8):837-42 [PMID] 3216963.
1988
Phorbol ester-induced upregulation of angiotensin II receptors in neuronal cultures is potentiated by a calcium ionophore.
Journal of neurochemistry. 51(1):153-62 [PMID] 3132530.
1988
Receptors for phorbol esters are primarily localized in neurons: comparison of neuronal and glial cultures.
Neurochemical research. 13(1):51-6 [PMID] 3368029.
1987
Angiotensin II inhibits the K+-evoked release of [3H]norepinephrine from hypothalamic synaptosomes of the spontaneously hypertensive rat.
Brain research. 403(1):167-71 [PMID] 3828811.
1987
Dipeptidyl peptidase-II activity in cultured astroglial cells from neonatal rat brain.
Brain research. 406(1-2):113-7 [PMID] 3552116.
1987
Distinct angiotensin II receptor in primary cultures of glial cells from rat brain.
Proceedings of the National Academy of Sciences of the United States of America. 84(13):4655-9 [PMID] 3474621.
1987
Insulin receptors and insulin action in dissociated brain cells.
Brain research. 417(2):247-56 [PMID] 3308002.
1987
Insulin-like growth factor I receptors in neuronal and glial cells. Characterization and biological effects in primary culture.
The Journal of biological chemistry. 262(16):7693-9 [PMID] 2953724.
1987
Norepinephrine metabolism in neuronal cultures is increased by angiotensin II.
The American journal of physiology. 252(6 Pt 1):C650-6 [PMID] 3591934.
1987
Norepinephrine regulation of alpha-1 receptors and alpha-1-stimulated phosphoinositide hydrolysis in primary neuronal cultures.
The Journal of pharmacology and experimental therapeutics. 242(3):764-71 [PMID] 2821226.
1987
Ontogeny of insulin receptors in the rat hemochorial placenta.
Developmental biology. 123(2):487-93 [PMID] 3308578.
1987
Phorbol esters inhibit agonist-stimulated phosphoinositide hydrolysis in neuronal primary cultures.
Brain research. 465(1-2):59-66 [PMID] 2894235.
1987
Phorbol esters stimulate 2-deoxyglucose uptake in glia, but not neurons.
Brain research. 421(1-2):358-62 [PMID] 3690278.
1987
Presence of renin in primary neuronal and glial cells from rat brain.
Brain research. 437(2):205-13 [PMID] 3325128.
1987
Protein kinase C agonists increase the expression of angiotensin II receptors in neuronal cultures.
Journal of neurochemistry. 48(6):1954-61 [PMID] 3572405.
1987
Structural and functional studies on insulin receptors from alligator brain and liver.
Comparative biochemistry and physiology. B, Comparative biochemistry. 86(1):55-61 [PMID] 3829632.
1986
Alpha 1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures.
Journal of neurochemistry. 47(4):1117-26 [PMID] 3018160.
1986
Alpha 1-adrenergic receptors in neuronal cultures from rat brain: increased expression in the spontaneously hypertensive rat.
Journal of neurochemistry. 47(4):1190-8 [PMID] 3018164.
1986
Angiotensin II stimulates norepinephrine uptake in hypothalamus-brain stem neuronal cultures.
The American journal of physiology. 250(2 Pt 1):C236-44 [PMID] 3513605.
1986
Changes in receptor stimulated phosphoinositide hydrolysis in brain during ethanol administration, aging, and other pathological conditions.
Psychopharmacology bulletin. 22(3):775-80 [PMID] 3025909.
1986
Characteristics of the beta-adrenoreceptor from neuronal and glial cells in primary cultures of rat brain.
Journal of neurochemistry. 47(4):1318-26 [PMID] 2875131.
1986
Decreased alpha 1-adrenergic receptor-mediated inositide hydrolysis in neurons from hypertensive rat brain.
The American journal of physiology. 251(2 Pt 1):C230-7 [PMID] 2874741.
1986
Development of brain insulin receptors: structural and functional studies of insulin receptors from whole brain and primary cell cultures.
Endocrinology. 119(1):25-35 [PMID] 3522210.
1986
Effects of AF64A on [3H]acetylcholine synthesis in neuron-enriched primary brain cell cultures.
Brain research. 395(1):110-3 [PMID] 3779427.
1986
Insulin inhibits specific norepinephrine uptake in neuronal cultures from rat brain.
Brain research. 398(1):1-5 [PMID] 3542120.
1986
Insulin is a growth-promoter of the developing brain: possible implications for the infant of the diabetic mother.
Comprehensive therapy. 12(1):57-61 [PMID] 3512157.
1986
Insulin is released from rat brain neuronal cells in culture.
Journal of neurochemistry. 47(3):831-6 [PMID] 3525754.
1986
Sodium increases angiotensin II receptors in neuronal cultures from brains of normotensive and hypertensive rats.
Brain research. 370(2):265-72 [PMID] 3011198.
1985
Altered norepinephrine uptake in neuronal cultures from spontaneously hypertensive rat brain.
The American journal of physiology. 248(5 Pt 1):C488-97 [PMID] 3993770.
1985
Developing rat brain binds monoiodinated insulin isomers similarly to other extrahepatic target tissues.
Brain research. 360(1-2):195-202 [PMID] 3907754.
1985
Increased turnover of surface insulin receptors in fibroblastic cultures from genetically diabetic (DB/DB) mice.
Journal of cellular biochemistry. 28(1):59-67 [PMID] 3897251.
1985
Insulin receptors and insulin modulation of norepinephrine uptake in neuronal cultures from rat brain.
The Journal of biological chemistry. 260(29):15880-4 [PMID] 3905797.
1985
Insulin stimulates macromolecular synthesis in cultured glial cells from rat brain.
The American journal of physiology. 249(5 Pt 1):C484-9 [PMID] 2415002.
1985
Receptor-mediated inositide hydrolysis is a neuronal response: comparison of primary neuronal and glial cultures.
Brain research. 345(2):350-5 [PMID] 2994846.
1984
Angiotensin II in neuronal cultures from brains of normotensive and hypertensive rats.
The American journal of physiology. 247(1 Pt 1):C115-9 [PMID] 6742179.
1984
Catecholamine-angiotensin II receptor interaction in primary cultures of rat brain.
The American journal of physiology. 246(5 Pt 1):C502-9 [PMID] 6144276.
1984
Increased angiotensin II receptors in neuronal cultures from hypertensive rat brain.
The American journal of physiology. 247(5 Pt 1):C364-72 [PMID] 6093569.
1984
Insulin binding in four regions of the developing rat brain.
Journal of neurochemistry. 42(1):198-203 [PMID] 6358413.
1984
Insulin binds to specific receptors and stimulates 2-deoxy-D-glucose uptake in cultured glial cells from rat brain.
The Journal of biological chemistry. 259(19):11672-5 [PMID] 6384211.
1984
Insulin inhibits pyramidal neurons in hippocampal slices.
Brain research. 309(1):187-91 [PMID] 6386100.
1984
The effects of insulin and tunicamycin on insulin receptors of cultured fibroblasts.
Experimental cell research. 151(2):533-41 [PMID] 6368251.
1983
Angiotensin II stimulates changes in the norepinephrine content of primary cultures of rat brain.
Neuroscience letters. 36(3):305-9 [PMID] 6866336.
1983
Cycloheximide causes accumulation of insulin receptors at the cell surface of cultured fibroblasts.
The Journal of biological chemistry. 258(21):13116-9 [PMID] 6355103.
1983
Effects of insulin and tunicamycin on neuronal insulin receptors in culture.
The American journal of physiology. 245(3):C283-7 [PMID] 6351631.
1983
Localization of insulin-like immunoreactivity in the neurons from primary cultures of rat brain.
Experimental cell research. 143(2):351-7 [PMID] 6339256.
1983
Primary cultures from fetal rat brain incorporate [3H]-isoleucine and [3H]-valine into immunoprecipitable angiotensin II.
Neuroendocrinology. 36(1):64-7 [PMID] 6828210.
1983
Rat brain cells in primary culture: visualization and measurement of catecholamines.
Brain research. 264(2):267-75 [PMID] 6850296.
1982
Adult-level insulin binding is present in term fetal rat CNS membranes.
Brain research. 249(2):390-2 [PMID] 6754002.
1982
Uptake of prolactin from cerebrospinal fluid in rat brain.
Neuropeptides. 3(2):173-9 [PMID] 6819487.
1981
Cytochalasin B-induced alterations of insulin binding and microfilament organization in cultured fibroblasts.
Experimental cell research. 136(2):335-41 [PMID] 7030757.
1981
Effects of insulin on cultured rat brain cells: stimulation of ornithine decarboxylase activity.
Journal of neurochemistry. 36(3):1050-7 [PMID] 7009787.
1981
Rat brain cells in primary culture: characterization of angiotensin II binding sites.
Brain research. 207(2):343-55 [PMID] 6258739.
1981
Trypsin-induced alterations of insulin binding, microfilament organization and cell shape in fibroblastic cultures from non-diabetic and diabetic mice.
Experimental cell research. 133(2):261-71 [PMID] 7195340.
1980
Alterations in the responsiveness of diabetic fibroblasts to insulin.
Journal of supramolecular structure. 14(4):499-509 [PMID] 7017281.
1980
Binding of [125I]insulin to specific receptors and stimulation of nucleotide incorporation in cells cultured from rat brain.
Brain research. 200(2):389-400 [PMID] 6158364.
1980
Cells cultured from the diabetic (DB/DB) mouse have a permanent decrease in insulin receptors.
Endocrinology. 107(5):1652-5 [PMID] 7000499.
1980
Fibroblastic cultures from the diabetic db/db mouse. Demonstration of decreased insulin receptors and impaired responses to insulin.
The Journal of biological chemistry. 255(19):9149-55 [PMID] 6997311.
1980
Increased specific binding of angiotensin II in the organum vasculosum of the laminae terminalis area of the spontaneously hypertensive rat brain.
Neuroscience letters. 17(1-2):173-7 [PMID] 7052462.
1980
Leucine-enkephalin immunoreactivity: localization in rat brain cells in culture.
Brain research. 181(2):465-9 [PMID] 6985810.
1980
Presence of angiotensin II in neurons cultured from fetal rat brain.
Neuroscience letters. 16(1):41-6 [PMID] 6763158.
1980
Visualization of specific angiotensin II binding sites in the brain by fluorescent microscopy.
Science (New York, N.Y.). 210(4471):791-3 [PMID] 6254147.
1979
Alteration of insulin binding and cytoskeletal organization in cultured fibroblasts by tertiary amine local anesthetics.
Journal of supramolecular structure. 11(4):547-61 [PMID] 232524.
1979
Decrease in insulin receptors during Friend erythroleukemia cell differentiation.
Diabetes. 28(9):823-7 [PMID] 288716.
1977
Formation of alpha-1,2-mannosyl-mannose by an enzyme preparation from rabbit liver.
The Journal of biological chemistry. 252(20):7235-42 [PMID] 903361.
1977
The effect of macrofixation on derepressed sugar transport systems of chick embryo fibroblasts.
Experimental cell research. 108(2):239-43 [PMID] 891638.
1976
Extent of mitogen receptor occupancy and modulation of mitogen receptor exposure: possible mechanisms for the regulation of cell growth.
Progress in clinical and biological research. 9:49-64 [PMID] 193133.
1976
Mitogen receptors in chick embryo fibroblasts. Kinetics, specificity, unmasking, and synthesis of 125I-insulin binding sites.
The Journal of biological chemistry. 251(20):6445-55 [PMID] 988022.
1975
The inhibitory effect of glucose on the differentiation of trophic Hartmannella culbertsoni into viable cysts.
Cell differentiation. 4(3):167-77 [PMID] 167987.
1974
Degradation of cysts of Hartmannella culbertsoni by culture filtrates of Alternaria sp.
Journal of general microbiology. 80(1):307-9 [PMID] 4856548.
1974
Effect of bioamines on the cellular differentiation of Hartmannella culbertsoni.
Biochemical pharmacology. 23(1):57-63 [PMID] 4359461.
1972
Transformation of trophic Hartmannella culbertsoni into viable cysts of cyclic 3′,5′-adenosine monophosphate.
The Journal of cell biology. 52(3):743-8 [PMID] 4333211.
1971
Changes in the activity of certain enzymes of Hartmannella (Culbertson strain A-1) during encystment.
The Journal of protozoology. 18(1):115-9 [PMID] 4251127.

Grants

Sep 2019 – Aug 2021
Optimization of food-grade recombinant probiotics for oral delivery of ACE2/Ang-(1-7)
Role: Principal Investigator
Funding: MEDOSOME BIOTEC via NATL INST OF HLTH NHLBI
May 2018 – Apr 2022
ACE2 Modulates the Bone Marrow- Gut Axis in Diabetic Retinopathy
Role: Project Manager
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NEI
Aug 2016 – Dec 2021
ACE2, Brain, Gut Dysbiosis in Pulmonary Hypertension
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Apr 2016 – Sep 2021
Brain-Gut Microbiome-Immune Axis in Hypertension
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jun 2014 – May 2017
Oral Delivery of Angiotensin Converting Enzyme 2 (ACE2) for Pulmonary Hypertension Therapeutics
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Jan 2014 – Jun 2018
Altered sympathetic activity to the bone marrow in neurogenic hypertension
Role: Project Manager
Funding: AMER HEART ASSOCIATION
Jul 2013 – May 2019
Angiotensin and neuroimmune activation in hypertension
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jan 2012 – Dec 2016
Ocular Renin Angotensin System in Pathogenesis of Diabetic Retinopathy
Role: Project Manager
Funding: NATL INST OF HLTH NEI
Mar 2011 – Feb 2017
CVD Protection Mechanism involving ACE2/ANG-(1-7) Axis
Role: Principal Investigator
Funding: NATL INST OF HLTH
May 2010 – Apr 2016
Angiotensin-Converting Enzyme2 in Vascular Endothelial Function
Role: Project Manager
Funding: NATL INST OF HLTH NHLBI

Contact Details

Phones:
Business:
(352) 392-9299
Emails:
Business:
mraizada@ufl.edu
Addresses:
Business Mailing:
PO Box 100274
GAINESVILLE FL 32610
Business Street:
L4181 UFBI
GAINESVILLE FL 32611